The French Guiana Régional 1 is the highest tier of men's football in French Guiana. It was created in 1961 and is organized by the Ligue de Football de la Guyane. There are twelve participants in the league, with teams finishing in the two bottom spots being relegated to the Régional 2. The division is equivalent to the sixth tier of football in France, the Régional 1.
Despite being a league competition in CONCACAF, none of the French Guianan teams have recently played in the Caribbean Club Championship or the CONCACAF Champions League. Their last appearance was in the 1992 CONCACAF Champions' Cup, represented by ASC Le Geldar.