The Premiership Rugby Cup is an English rugby union knockout cup competition for teams in Premiership Rugby and from the 2023–24 season the RFU Championship. It was created in 2018 to replace the Anglo-Welsh Cup after the withdrawal of the Welsh regions.
The Premiership Rugby Cup was created to replace the Anglo-Welsh Cup which had been running since 2005 when the Welsh regions joined the then English-only Powergen Cup. In the 2017–18 Anglo-Welsh Cup, all four of the Welsh regions finished bottom of their pools. In May 2018, the Welsh Rugby Union announced that they were going to be setting up a Welsh under-23s competition for their regions and would thus be unable to commit to Anglo-Welsh Cup games. Premiership Rugby Limited, which organises the English top flight, then announced that the Anglo-Welsh Cup would be replaced by the Premiership Rugby Cup, which would be solely for the English Premiership clubs. The new Premiership Cup was created to re-establish the significance of the domestic cup competition and support development of younger English Premiership players by providing a platform to compete in more matches at Premiership stadia.
The 2020–21 tournament was cancelled due to the effects of the COVID-19 pandemic.