Head to Head
| NCAAF | 2008/08/30 12:00 | Southern Mississippi v Lafayette | W | 51-21 |
| NCAAF | 2003/11/01 12:00 | Southern Mississippi v Lafayette | W | 48-3 |
| NCAAF | 2001/09/22 12:00 | Lafayette v Southern Mississippi | W | 10-35 |
Home History
| NCAAF | 2016/11/25 21:00 | Louisiana Tech v Southern Mississippi | W | 24-39 |
| NCAAF | 2016/11/19 22:30 | Southern Mississippi v North Texas | L | 23-29 |
| NCAAF | 2016/11/12 20:30 | Southern Mississippi v Old Dominion | L | 35-51 |
| NCAAF | 2016/11/05 19:30 | Charlotte v Southern Mississippi | L | 38-27 |
| NCAAF | 2016/10/29 23:00 | Marshall v Southern Mississippi | W | 14-24 |
| NCAAF | 2016/10/15 23:30 | Southern Mississippi v LSU | L | 10-45 |
| NCAAF | 2016/10/08 16:00 | Southern Mississippi v Texas-San Antonio | L | 32-55 |
| NCAAF | 2016/10/01 23:00 | Rice v Southern Mississippi | W | 28-44 |
Away History
| NCAAF | 2016/12/03 20:00 | Lafayette v UL Monroe | W | 30-3 |
| NCAAF | 2016/11/26 17:00 | Arkansas State v Lafayette | W | 19-24 |
| NCAAF | 2016/11/19 17:00 | Lafayette v Georgia | L | 21-35 |
| NCAAF | 2016/11/11 00:30 | Lafayette v Georgia Southern | W | 33-26 |
| NCAAF | 2016/11/05 21:00 | Idaho v Lafayette | L | 23-13 |
| NCAAF | 2016/10/22 23:00 | Lafayette v Texas State | W | 27-3 |
| NCAAF | 2016/10/15 16:00 | Lafayette v Army | L | 7-62 |
| NCAAF | 2016/10/13 00:00 | Appalachian St v Lafayette | L | 24-0 |