Head to Head
| England Premier League 2 | 2018/08/24 18:00 | Southampton U23 v Man Utd U23 | D | 1-1 |
| England Premier League 2 | 2017/03/13 19:00 | Man Utd U23 v Southampton U23 | D | 3-3 |
Home History
| England Premier League 2 | 2019/01/11 19:00 | Man Utd U23 v Fulham U23 | L | 1-3 |
| England Premier League 2 | 2019/01/07 19:00 | Aston Villa U23 v Man Utd U23 | L | 5-1 |
| England Premier League 2 | 2018/12/16 13:00 | Reading U23 v Man Utd U23 | W | 0-1 |
| England Premier League 2 | 2018/12/07 19:00 | Man Utd U23 v Middlesbrough U23 | W | 2-0 |
| England Premier League 2 | 2018/11/23 19:00 | West Brom U23 v Man Utd U23 | D | 1-1 |
| England Premier League 2 | 2018/11/02 19:00 | Man Utd U23 v Newcastle U23 | L | 1-4 |
| England Premier League 2 | 2018/10/26 18:00 | Wolverhampton U23 v Man Utd U23 | L | 2-1 |
| England Premier League 2 | 2018/10/19 18:00 | Man Utd U23 v Sunderland U23 | W | 3-0 |
Away History
| England U23 Premier League Cup | 2019/01/21 19:01 | Leeds U23 v Southampton U23 | L | 3-2 |
| England Premier League 2 | 2019/01/13 13:00 | Middlesbrough U23 v Southampton U23 | W | 1-2 |
| England Premier League 2 | 2019/01/04 19:00 | Southampton U23 v Stoke U23 | W | 2-0 |
| England Premier League 2 | 2018/12/14 19:00 | Southampton U23 v Newcastle U23 | W | 2-1 |
| England Premier League 2 | 2018/12/07 19:00 | Aston Villa U23 v Southampton U23 | L | 2-1 |
| England U23 Premier League Cup | 2018/11/28 13:58 | Notts County U23 v Southampton U23 | W | 0-7 |
| England U23 Premier League Cup | 2018/11/09 19:00 | Southampton U23 v Newcastle U23 | D | 1-1 |
| England Premier League 2 | 2018/11/02 19:00 | Southampton U23 v West Brom U23 | W | 1-0 |