| Uruguay Reserve League | 2018/05/08 18:00 | Penarol Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2017/10/24 18:00 | Penarol Reserves v Defensor Sporting Reserves | W | 2-3 |
| Uruguay Reserve League | 2018/10/24 13:00 | Atletico River Plate Reserves v Defensor Sporting Reserves | D | 3-3 |
| Uruguay Reserve League | 2018/10/16 13:00 | Liverpool Montevideo Reserves v Defensor Sporting Reserves | L | 1-0 |
| Uruguay Reserve League | 2018/10/10 18:30 | Torque Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2018/10/07 16:30 | Defensor Sporting Reserves v Montevideo Wanderers Reserves | W | 3-1 |
| Uruguay Reserve League | 2018/09/19 18:30 | Defensor Sporting Reserves v Racing Club de Montevideo Reserves | D | 1-1 |
| Uruguay Reserve League | 2018/09/11 13:00 | CA Cerro Reserves v Defensor Sporting Reserves | L | 4-2 |
| Uruguay Reserve League | 2018/09/04 13:00 | Progreso Reserves v Defensor Sporting Reserves | W | 0-4 |
| Uruguay Reserve League | 2018/08/28 13:30 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | W | 2-0 |
| Uruguay Reserve League | 2018/10/30 13:00 | Penarol Reserves v Progreso Reserves | W | 4-2 |
| Uruguay Reserve League | 2018/10/20 15:15 | Nacional de Montevideo Reserves v Penarol Reserves | L | 4-0 |
| Uruguay Reserve League | 2018/10/16 13:00 | Penarol Reserves v Atletico Fenix Reserves | W | 4-0 |
| Uruguay Reserve League | 2018/09/30 17:37 | Rampla Juniors Reserves v Penarol Reserves | D | 0-0 |
| Uruguay Reserve League | 2018/09/26 13:00 | Penarol Reserves v Torque Reserves | W | 2-1 |
| Uruguay Reserve League | 2018/09/19 18:00 | Danubio Reserves v Penarol Reserves | D | 1-1 |
| Uruguay Reserve League | 2018/09/12 14:00 | Penarol Reserves v Atenas Reserves | W | 3-0 |
| Uruguay Reserve League | 2018/09/05 13:00 | Penarol Reserves v CA Cerro Reserves | W | 3-1 |