Stadium: Exactech Arena at the Stephen C. O'Connell Center Round: 1
Home Manager: Mike White Away Manager: Tom Izzo
| NCAAB | 2015/12/12 23:00 | Michigan State v Florida Gators | W | 58-52 |
| NCAAB | 2009/11/27 12:00 | Florida Gators v Michigan State | L | 77-74 |
| NCAAB | 2003/03/23 12:00 | Michigan State v Florida Gators | W | 68-46 |
| NCAAB | 2018/12/03 23:30 | Iowa v Michigan State | W | 68-90 |
| NCAAB | 2018/11/30 23:00 | Michigan State v Rutgers | W | 78-67 |
| NCAAB | 2018/11/28 00:30 | Michigan State v Louisville | L | 78-82 |
| NCAAB | 2018/11/23 23:30 | Texas v Michigan State | W | 68-78 |
| NCAAB | 2018/11/23 03:00 | Michigan State v UCLA | W | 87-67 |
| NCAAB | 2018/11/18 23:00 | Tennessee Tech v Michigan State | W | 33-101 |
| NCAAB | 2018/11/15 00:00 | UL Monroe v Michigan State | W | 59-80 |
| NCAAB | 2018/11/11 23:00 | Florida Gulf Coast v Michigan State | W | 82-106 |
| NCAAB | 2018/12/05 02:00 | West Virginia v Florida Gators | W | 56-66 |
| NCAAB | 2018/11/28 00:00 | North Florida v Florida Gators | W | 66-98 |
| NCAAB | 2018/11/24 02:30 | Florida Gators v Butler | L | 54-61 |
| NCAAB | 2018/11/23 00:00 | Florida Gators v Stanford | W | 72-49 |
| NCAAB | 2018/11/21 17:00 | Florida Gators v Oklahoma | L | 60-65 |
| NCAAB | 2018/11/15 00:00 | La Salle v Florida Gators | W | 69-82 |
| NCAAB | 2018/11/10 00:00 | Charleston Southern v Florida Gators | W | 46-76 |
| NCAAB | 2018/11/07 02:00 | Florida Gators v Florida State | L | 60-81 |