Stadium: Winthrop Coliseum Round: 1
Home Manager: Pat Kelsey Away Manager: Byron Smith
| NCAAB | 2018/12/21 03:00 | Prairie View v Seattle | L | 64-102 |
| NCAAB | 2018/12/12 01:00 | Prairie View v UL Lafayette | L | 90-122 |
| NCAAB | 2018/12/05 00:30 | Prairie View v Louisiana Tech | L | 68-82 |
| NCAAB | 2018/12/02 01:00 | Prairie View v Murray State | L | 67-83 |
| NCAAB | 2018/11/23 21:00 | Prairie View v Georgia Tech | L | 54-65 |
| NCAAB | 2018/11/22 00:00 | Prairie View v East Carolina | L | 64-76 |
| NCAAB | 2018/11/20 00:00 | Prairie View v NC Greensboro | L | 66-74 |
| NCAAB | 2018/11/17 20:00 | Prairie View v Lamar | L | 67-74 |
| NCAAB | 2018/12/22 21:00 | Winthrop v Southern Illinois | W | 79-71 |
| NCAAB | 2018/12/20 16:00 | Maryland Eastern-Shore v Winthrop | W | 74-88 |
| NCAAB | 2018/12/16 19:00 | Hiwassee College v Winthrop | W | 66-109 |
| NCAAB | 2018/12/05 00:00 | Winthrop v Davidson | L | 81-99 |
| NCAAB | 2018/11/29 00:00 | Winthrop v Tennessee Tech | W | 82-70 |
| NCAAB | 2018/11/24 19:00 | Warren Wilson v Winthrop | W | 76-116 |
| NCAAB | 2018/11/21 18:00 | Winthrop v Kentucky | L | 74-87 |
| NCAAB | 2018/11/17 19:30 | East Tenn St v Winthrop | L | 76-74 |