Stadium: Mohegan Sun Arena Round: 1
Home Manager: Jamion Christian Away Manager: Bill Carmody
| NCAAB | 2017/12/23 00:00 | Siena v Holy Cross | L | 71-65 |
| NCAAB | 2008/12/30 12:00 | Holy Cross v Siena | L | 71-83 |
| NCAAB | 2007/12/22 12:00 | Siena v Holy Cross | L | 84-77 |
| NCAAB | 2006/11/18 12:00 | Holy Cross v Siena | W | 65-57 |
| NCAAB | 2005/12/01 12:00 | Siena v Holy Cross | L | 68-63 |
| NCAAB | 2018/11/16 23:00 | Stony Brook v Holy Cross | W | 70-84 |
| NCAAB | 2018/11/14 00:00 | Holy Cross v Providence | L | 61-70 |
| NCAAB | 2018/11/11 00:30 | Holy Cross v Michigan | L | 37-56 |
| NCAAB | 2018/11/07 00:05 | Sacred Heart v Holy Cross | W | 81-93 |
| NCAAB | 2018/03/04 17:00 | Holy Cross v Colgate | L | 55-62 |
| NCAAB | 2018/03/02 00:00 | Holy Cross v Navy | W | 81-65 |
| NCAAB | 2018/02/24 19:00 | Colgate v Holy Cross | L | 59-53 |
| NCAAB | 2018/02/22 00:05 | American v Holy Cross | W | 64-70 |
| NCAAB | 2018/11/17 01:30 | Norfolk State v Siena | W | 58-61 |
| NCAAB | 2018/11/09 00:00 | Siena v George Washington | W | 69-61 |
| NCAAB | 2018/11/06 23:30 | Siena v Providence | L | 67-77 |
| NCAAB | 2018/03/02 01:18 | Siena v Quinnipiac | L | 58-67 |
| NCAAB | 2018/02/25 19:00 | Siena v St. Peter's | L | 48-65 |
| NCAAB | 2018/02/22 00:00 | Fairfield v Siena | L | 70-69 |
| NCAAB | 2018/02/18 19:00 | Monmouth v Siena | L | 93-89 |
| NCAAB | 2018/02/16 00:00 | Siena v Rider | L | 71-97 |