Stadium: Littlejohn Coliseum Round: 1
Home Manager: Brad Brownell Away Manager: Barclay Radebaugh
| NCAAB | 2006/11/24 12:00 | Clemson v Charleston Southern | L | 74-50 |
| NCAAB | 2005/11/26 12:00 | Charleston Southern v Clemson | L | 56-68 |
| NCAAB | 2004/12/11 12:00 | Clemson v Charleston Southern | L | 73-55 |
| NCAAB | 2018/12/15 22:00 | Charleston Southern v North Florida | L | 61-68 |
| NCAAB | 2018/12/12 00:00 | Charleston Southern v Furman | L | 69-77 |
| NCAAB | 2018/12/01 22:30 | North Florida v Charleston Southern | L | 76-70 |
| NCAAB | 2018/11/28 01:00 | Charleston Southern v Marquette | L | 55-76 |
| NCAAB | 2018/11/23 20:30 | Coppin State v Charleston Southern | W | 67-93 |
| NCAAB | 2018/11/20 00:30 | Charleston Southern v Trinity Baptist | W | 98-49 |
| NCAAB | 2018/11/17 00:30 | Charleston Southern v Middle Tenn St | L | 73-76 |
| NCAAB | 2018/11/14 00:30 | South Carolina State v Charleston Southern | W | 72-89 |
| NCAAB | 2018/12/15 20:00 | Radford v Clemson | W | 66-74 |
| NCAAB | 2018/12/08 21:00 | Mississippi State v Clemson | L | 82-71 |
| NCAAB | 2018/12/05 00:00 | St. Peter's v Clemson | W | 60-65 |
| NCAAB | 2018/11/27 00:00 | Nebraska v Clemson | L | 68-66 |
| NCAAB | 2018/11/22 00:30 | Clemson v Creighton | L | 82-87 |
| NCAAB | 2018/11/20 18:30 | Clemson v Georgia Bulldogs | W | 64-49 |
| NCAAB | 2018/11/19 16:00 | Akron v Clemson | W | 69-72 |
| NCAAB | 2018/11/15 00:00 | Sam Houston State v Clemson | W | 59-74 |