Stadium: Dana J. Dykhouse Stadium Round: 8
Home Manager: John Stiegelmeier Away Manager: Jerry Schmitt
| NCAAF FCS | 2018/11/24 19:00 | Duquesne v Towson | W | 31-10 |
| NCAAF FCS | 2018/11/17 17:00 | Duquesne v Central Connecticut | W | 38-31 |
| NCAAF | 2018/11/10 17:00 | Duquesne v Sacred Heart | W | 28-24 |
| NCAAF FCS | 2018/11/03 16:00 | Duquesne v Wagner | W | 47-30 |
| NCAAF | 2018/10/20 16:00 | St.Francis (PA) v Duquesne | W | 20-27 |
| NCAAF | 2018/10/13 23:00 | Robert Morris v Duquesne | W | 24-48 |
| NCAAF | 2018/10/06 17:00 | Bryant v Duquesne | L | 21-20 |
| NCAAF | 2018/09/23 04:00 | Duquesne v Hawaii | L | 21-42 |
| NCAAF FCS | 2018/11/17 20:00 | South Dakota v South Dakota State | W | 27-49 |
| NCAAF FCS | 2018/11/10 19:00 | South Dakota State v SO Illinois | W | 57-38 |
| NCAAF FCS | 2018/11/03 19:00 | Missouri St v South Dakota State | W | 7-59 |
| NCAAF | 2018/10/27 17:00 | Illinois State v South Dakota State | W | 28-38 |
| NCAAF | 2018/10/20 21:00 | Northern Iowa v South Dakota State | L | 24-9 |
| NCAAF | 2018/10/13 19:00 | Youngstown State v South Dakota State | W | 7-36 |
| NCAAF | 2018/10/06 23:00 | Indiana State v South Dakota State | W | 51-54 |
| NCAAF | 2018/09/29 19:30 | South Dakota State v North Dakota State | L | 17-21 |