[16] BUF Sabres 2-4 FLA Panthers [24] 2019-02-20 00:00
Stadium: Amerant Bank Arena Round: 1
Home Manager: Bob Boughner Away Manager: Phil Housley
Head to Head
| NHL | 2019/01/04 00:00 | FLA Panthers v BUF Sabres | W | 3-4 |
| NHL | 2018/12/19 00:00 | FLA Panthers v BUF Sabres | L | 5-2 |
| NHL | 2018/12/01 00:00 | BUF Sabres v FLA Panthers | L | 2-3 |
| NHL | 2018/04/07 23:00 | BUF Sabres v FLA Panthers | L | 3-4 |
| NHL | 2018/03/03 00:30 | BUF Sabres v FLA Panthers | L | 1-4 |
| NHL | 2018/02/02 00:00 | FLA Panthers v BUF Sabres | L | 4-2 |
| NHL | 2017/11/11 00:00 | FLA Panthers v BUF Sabres | L | 4-1 |
| NHL | 2017/04/08 23:00 | BUF Sabres v FLA Panthers | L | 0-3 |
Home History
| NHL | 2019/02/17 23:00 | BUF Sabres v NJ Devils | L | 1-4 |
| NHL | 2019/02/16 00:00 | NY Rangers v BUF Sabres | L | 6-2 |
| NHL | 2019/02/13 00:00 | NY Islanders v BUF Sabres | W | 1-3 |
| NHL | 2019/02/10 20:00 | WIN Jets v BUF Sabres | L | 3-1 |
| NHL | 2019/02/09 18:00 | DET Red Wings v BUF Sabres | W | 1-3 |
| NHL | 2019/02/08 00:00 | CAR Hurricanes v BUF Sabres | L | 6-5 |
| NHL | 2019/02/06 00:00 | MIN Wild v BUF Sabres | W | 4-5 |
| NHL | 2019/02/02 00:00 | CHI Blackhawks v BUF Sabres | L | 7-3 |
Away History
| NHL | 2019/02/18 00:00 | MON Canadiens v FLA Panthers | W | 3-6 |
| NHL | 2019/02/15 00:00 | CAL Flames v FLA Panthers | W | 2-3 |
| NHL | 2019/02/13 00:00 | DAL Stars v FLA Panthers | L | 3-0 |
| NHL | 2019/02/10 23:00 | TB Lightning v FLA Panthers | L | 5-2 |
| NHL | 2019/02/10 00:00 | FLA Panthers v WAS Capitals | W | 5-4 |
| NHL | 2019/02/08 00:00 | PIT Penguins v FLA Panthers | W | 2-3 |
| NHL | 2019/02/06 00:00 | STL Blues v FLA Panthers | L | 3-2 |
| NHL | 2019/02/03 00:00 | VGS Golden Knights v FLA Panthers | W | 1-3 |