Head to Head
| NCAAF | 2014/09/06 16:30 | Clemson v South Carolina State | W | 73-7 |
| NCAAF | 2008/09/20 12:00 | Clemson v South Carolina State | W | 54-0 |
Home History
| NCAAF | 2016/09/10 16:30 | Clemson v Troy | W | 30-24 |
| NCAAF | 2016/09/04 01:00 | Clemson v Auburn | W | 19-13 |
| NCAAF | 2016/01/12 01:30 | Clemson v Alabama | L | 40-45 |
| NCAAF | 2015/12/31 21:00 | Clemson v Oklahoma | W | 37-17 |
| NCAAF | 2015/12/06 01:00 | Clemson v North Carolina | W | 45-37 |
| NCAAF | 2015/11/28 17:00 | South Carolina v Clemson | W | 32-37 |
| NCAAF | 2015/11/21 20:30 | Clemson v Wake Forest | W | 33-13 |
| NCAAF | 2015/11/14 20:30 | Syracuse v Clemson | W | 27-37 |
Away History
| NCAAF | 2016/09/10 23:00 | Louisiana Tech v South Carolina State | L | 53-24 |
| NCAAF | 2016/09/03 23:00 | Central Florida v South Carolina State | L | 38-0 |
| NCAAF | 2014/09/06 16:30 | Clemson v South Carolina State | L | 73-7 |
| NCAAF | 2012/09/22 12:00 | Texas A&M v South Carolina State | L | 70-14 |
| NCAAF | 2012/09/15 12:00 | Arizona v South Carolina State | L | 56-0 |
| NCAAF | 2011/09/17 12:00 | Indiana v South Carolina State | L | 38-21 |
| NCAAF | 2011/09/01 12:00 | Central Michigan v South Carolina State | L | 21-6 |
| NCAAF | 2010/09/04 12:00 | Georgia Tech v South Carolina State | L | 41-10 |