[57] Dayana Yastremska 2-6,1-6 Serena Williams [16] 2019-01-19 03:25
Stadium: Rod Laver Arena Round: 25 Ground: Hardcourt outdoor
Home History
| Australian Open Women | 2019/01/17 09:00 | Carla Suarez Navarro v Dayana Yastremska | 3-6,6-3,1-6 |
| Australian Open Women | 2019/01/15 06:50 | Samantha Stosur v Dayana Yastremska | 5-7,2-6 |
| WTA Hobart | 2019/01/10 07:00 | Dayana Yastremska v Belinda Bencic | 6-7,3-6 |
| WTA Hobart | 2019/01/09 01:45 | Vera Lapko v Dayana Yastremska | 1-6,4-6 |
| WTA Hobart | 2019/01/07 03:30 | Laura Siegemund v Dayana Yastremska | 3-6,1-6 |
| WTA Brisbane | 2018/12/28 02:40 | Dayana Yastremska v Varvara Lepchenko | 3-6,6-1,6-4 |
| WTA Luxembourg | 2018/10/19 17:35 | Belinda Bencic v Dayana Yastremska | 6-2,3-6,7-6 |
| WTA Luxembourg | 2018/10/18 12:35 | Margarita Betova v Dayana Yastremska | 1-6,4-6 |
Away History
| Australian Open Women | 2019/01/17 09:20 | Eugenie Bouchard v Serena Williams | 2-6,2-6 |
| Australian Open Women | 2019/01/15 01:35 | Tatjana Maria v Serena Williams | 0-6,2-6 |
| Hopman Cup Women | 2019/01/03 03:30 | Katie Boulter v Serena Williams | 1-6,6-7 |
| Hopman Cup Women | 2019/01/01 10:45 | Serena Williams v Belinda Bencic | 4-6,6-4,6-3 |
| Hopman Cup Women | 2018/12/31 04:30 | Serena Williams v Maria Sakkari | 7-6,6-2 |
| Mubadala World Tennis Championship Women | 2018/12/27 16:05 | Serena Williams v Venus Williams | 6-4,3-6,8-10 |
| US Open Women | 2018/09/08 20:00 | Serena Williams v Naomi Osaka | 2-6,4-6 |
| US Open Women | 2018/09/06 23:10 | Serena Williams v Anastasija Sevastova | 6-3,6-0 |