[72] Nick Kyrgios 7-5,5-7,7-6 John Isner [9] 2019-03-02 04:30
Stadium: Cancha Central Round: 28 Ground: Hardcourt outdoor
Head to Head
| Davis Cup | 2017/04/07 05:30 | Nick Kyrgios v John Isner | 7-5,7-6,7-6 |
| ATP Montreal | 2015/08/13 20:35 | Nick Kyrgios v John Isner | 5-7,3-6 |
| ATP Madrid | 2015/05/07 12:50 | Nick Kyrgios v John Isner | 3-6,7-6,4-6 |
Home History
| ATP Acapulco | 2019/03/01 02:20 | Nick Kyrgios v Stan Wawrinka | 7-5,6-7,6-4 |
| ATP Acapulco | 2019/02/28 01:55 | Rafael Nadal v Nick Kyrgios | 6-3,6-7,6-7 |
| ATP Acapulco | 2019/02/27 00:00 | Nick Kyrgios v Andreas Seppi | 6-3,7-5 |
| ATP Delray Beach | 2019/02/21 20:20 | Radu Albot v Nick Kyrgios | 6-2,3-6,6-3 |
| ATP Delray Beach | 2019/02/19 01:00 | Nick Kyrgios v John Millman | 6-4,6-7,7-6 |
| Australian Open | 2019/01/15 08:35 | Nick Kyrgios v Milos Raonic | 4-6,6-7,4-6 |
| Kooyong Classic | 2019/01/09 02:20 | Bernard Tomic v Nick Kyrgios | 6-3,6-4 |
| Fast 4 Tennis | 2019/01/07 08:30 | Nick Kyrgios v Rafael Nadal | 4-0,3-4,5-3 |
Away History
| ATP Acapulco | 2019/03/01 05:10 | John Isner v John Millman | 7-6,6-7,7-6 |
| ATP Acapulco | 2019/02/27 22:00 | John Isner v Sam Querrey | 6-4,6-4 |
| ATP Acapulco | 2019/02/26 22:00 | John Isner v Adrian Mannarino | 6-3,4-6,6-3 |
| ATP Delray Beach | 2019/02/23 20:00 | Daniel Evans v John Isner | 3-6,6-2,6-3 |
| ATP Delray Beach | 2019/02/22 19:30 | Adrian Mannarino v John Isner | 6-7,4-6 |
| ATP Delray Beach | 2019/02/20 23:00 | Lukas Lacko v John Isner | 4-6,3-6 |
| ATP Delray Beach | 2019/02/19 20:05 | Peter Polansky v John Isner | 3-6,6-7 |
| ATP New York | 2019/02/17 00:00 | John Isner v Reilly Opelka | 7-6,6-7,6-7 |