[9] John Isner 4-6,6-7 Karen Khachanov [13] 2019-03-13 21:10
Stadium: Stadium 2 Round: 26 Ground: Hardcourt outdoor
Head to Head
| ATP Paris | 2018/11/01 12:00 | Karen Khachanov v John Isner | 6-4,6-7,7-6 |
| ATP Toronto | 2018/08/09 22:40 | Karen Khachanov v John Isner | 7-6,7-6 |
| French Open | 2017/06/03 14:15 | John Isner v Karen Khachanov | 6-7,3-6,7-6,6-7 |
Home History
| ATP Indian Wells | 2019/03/12 21:20 | John Isner v Guido Pella | 6-3,6-4 |
| ATP Indian Wells | 2019/03/10 23:15 | John Isner v Alexei Popyrin | 6-0,6-2 |
| ATP Acapulco | 2019/03/02 04:30 | Nick Kyrgios v John Isner | 7-5,5-7,7-6 |
| ATP Acapulco | 2019/03/01 05:10 | John Isner v John Millman | 7-6,6-7,7-6 |
| ATP Acapulco | 2019/02/27 22:00 | John Isner v Sam Querrey | 6-4,6-4 |
| ATP Acapulco | 2019/02/26 22:00 | John Isner v Adrian Mannarino | 6-3,4-6,6-3 |
| ATP Delray Beach | 2019/02/23 20:00 | Daniel Evans v John Isner | 3-6,6-2,6-3 |
| ATP Delray Beach | 2019/02/22 19:30 | Adrian Mannarino v John Isner | 6-7,4-6 |
Away History
| ATP Indian Wells | 2019/03/12 22:45 | Andrey Rublev v Karen Khachanov | 5-7,3-6 |
| ATP Indian Wells | 2019/03/11 00:05 | Feliciano Lopez v Karen Khachanov | 3-6,6-1,4-6 |
| ATP Dubai | 2019/02/25 12:20 | Nikoloz Basilashvili v Karen Khachanov | 6-4,6-1 |
| ATP Rotterdam | 2019/02/12 21:00 | Tallon Griekspoor v Karen Khachanov | 3-6,6-3,6-2 |
| ATP Sofia | 2019/02/06 18:10 | Karen Khachanov v Matteo Berrettini | 7-6,3-6,4-6 |
| Davis Cup | 2019/02/02 15:10 | Henri Laaksonen v Karen Khachanov | 7-6,6-7,4-6 |
| Davis Cup | 2019/02/01 15:45 | Marc-Andrea Huesler v Karen Khachanov | 3-6,5-7 |
| Australian Open | 2019/01/18 07:20 | Roberto Bautista-Agut v Karen Khachanov | 6-4,7-5,6-4 |