[5] Monterrey 4-0 Santos Laguna [12] 2019-04-15 01:30
Weather: Good Stadium: Estadio BBVA Bancomer Pitch: Good Round: 14
Referee: Luis Enrique Santander Aguirre Home Manager: Diego Alonso Away Manager: Salvador Reyes
Head to Head
| Mexico Liga MX | 2018/12/02 03:00 | Santos Laguna v Monterrey | W | 0-2 |
| Mexico Liga MX | 2018/11/29 03:06 | Monterrey v Santos Laguna | W | 1-0 |
| Mexico Liga MX | 2018/10/27 00:00 | Santos Laguna v Monterrey | L | 1-0 |
| Mexico Liga MX | 2018/03/12 00:00 | Santos Laguna v Monterrey | L | 3-2 |
| Mexico Liga MX | 2017/11/10 03:00 | Monterrey v Santos Laguna | D | 1-1 |
| Mexico Cup | 2017/11/02 01:00 | Monterrey v Santos Laguna | W | 4-1 |
| Mexico Liga MX | 2017/09/28 02:00 | Monterrey v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2017/04/13 00:30 | Santos Laguna v Monterrey | D | 2-2 |
Home History
| CONCACAF Champions Cup | 2019/04/12 01:00 | Sporting Kansas City v Monterrey | W | 2-5 |
| Mexico Liga MX | 2019/04/07 17:00 | Toluca v Monterrey | L | 5-1 |
| CONCACAF Champions Cup | 2019/04/05 02:00 | Monterrey v Sporting Kansas City | W | 5-0 |
| Mexico Liga MX | 2019/03/31 03:00 | Monterrey v Cruz Azul | D | 2-2 |
| World Club Friendlies | 2019/03/23 23:45 | San Jose Earthquakes v Monterrey | W | 1-2 |
| Mexico Liga MX | 2019/03/17 03:06 | Tijuana v Monterrey | L | 1-0 |
| CONCACAF Champions Cup | 2019/03/14 00:00 | Atlanta United v Monterrey | L | 1-0 |
| Mexico Liga MX | 2019/03/10 01:00 | Monterrey v Tigres UANL | D | 1-1 |
Away History
| CONCACAF Champions Cup | 2019/04/11 00:00 | Santos Laguna v Tigres UANL | W | 3-2 |
| Mexico Liga MX | 2019/04/07 23:06 | Santos Laguna v Pachuca | D | 0-0 |
| CONCACAF Champions Cup | 2019/04/04 02:00 | Tigres UANL v Santos Laguna | L | 3-0 |
| Mexico Liga MX | 2019/03/30 03:00 | Atlas v Santos Laguna | L | 1-0 |
| Mexico Liga MX | 2019/03/18 00:06 | Santos Laguna v Necaxa | L | 1-2 |
| CONCACAF Champions Cup | 2019/03/13 01:00 | Santos Laguna v New York Red Bulls | W | 4-2 |
| Mexico Liga MX | 2019/03/09 01:00 | Veracruz v Santos Laguna | D | 2-2 |
| CONCACAF Champions Cup | 2019/03/06 01:00 | New York Red Bulls v Santos Laguna | W | 0-2 |