[23] Clemson 21-20 North Carolina [21] 2019-09-28 19:30
Stadium: Kenan Stadium Round: 1
Home Manager: Away Manager: Dabo Swinney
Head to Head
| NCAAF | 2015/12/06 01:00 | Clemson v North Carolina | W | 45-37 |
| NCAAF | 2014/09/27 23:00 | Clemson v North Carolina | W | 50-35 |
| NCAAF | 2011/10/22 12:00 | Clemson v North Carolina | W | 59-38 |
| NCAAF | 2010/10/09 12:00 | North Carolina v Clemson | L | 21-16 |
| NCAAF | 2006/09/23 12:00 | Clemson v North Carolina | W | 52-7 |
| NCAAF | 2003/10/25 12:00 | Clemson v North Carolina | W | 36-28 |
| NCAAF | 2002/11/09 12:00 | North Carolina v Clemson | W | 12-42 |
| NCAAF | 2001/10/20 12:00 | Clemson v North Carolina | L | 3-38 |
Home History
| NCAAF | 2019/09/21 23:30 | Charlotte v Clemson | W | 10-52 |
| NCAAF | 2019/09/14 23:30 | Clemson v Syracuse | W | 41-6 |
| NCAAF | 2019/09/07 19:30 | Texas A&M v Clemson | W | 10-24 |
| NCAAF | 2019/08/30 00:00 | Georgia Tech v Clemson | W | 14-52 |
| NCAAF | 2019/01/08 01:00 | Clemson v Alabama | W | 44-16 |
| NCAAF | 2018/12/29 21:00 | Notre Dame v Clemson | W | 3-30 |
| NCAAF | 2018/12/02 01:00 | Pittsburgh v Clemson | W | 10-42 |
| NCAAF | 2018/11/25 00:00 | South Carolina v Clemson | W | 35-56 |
Away History
| NCAAF | 2019/09/21 19:30 | Appalachian St v North Carolina | L | 34-31 |
| NCAAF | 2019/09/13 22:00 | North Carolina v Wake Forest | L | 18-24 |
| NCAAF | 2019/09/08 00:00 | Miami Florida v North Carolina | W | 25-28 |
| NCAAF | 2019/08/31 19:30 | South Carolina v North Carolina | W | 20-24 |
| NCAAF | 2018/11/24 17:20 | NC State v North Carolina | L | 34-28 |
| NCAAF | 2018/11/17 20:00 | Western Carolina v North Carolina | W | 26-49 |
| NCAAF | 2018/11/10 17:20 | North Carolina v Duke | L | 35-42 |
| NCAAF | 2018/11/03 16:15 | Georgia Tech v North Carolina | L | 38-28 |