[36] Iowa State 41-42 Oklahoma [13] 2019-11-10 01:00
Stadium: Gaylord Family Oklahoma Memorial Stadium Round: 1
Home Manager: Lincoln Riley Away Manager: Matt Campbell
Head to Head
| NCAAF | 2018/09/15 16:00 | Oklahoma v Iowa State | L | 37-27 |
| NCAAF | 2017/10/07 16:00 | Iowa State v Oklahoma | W | 38-31 |
| NCAAF | 2016/11/03 23:30 | Oklahoma v Iowa State | L | 34-24 |
| NCAAF | 2015/11/08 00:00 | Oklahoma v Iowa State | L | 52-16 |
| NCAAF | 2014/11/01 16:00 | Iowa State v Oklahoma | L | 14-59 |
| NCAAF | 2012/11/03 12:00 | Iowa State v Oklahoma | L | 20-35 |
| NCAAF | 2011/11/26 12:00 | Oklahoma v Iowa State | L | 26-6 |
| NCAAF | 2010/10/16 12:00 | Oklahoma v Iowa State | L | 52-0 |
Home History
| NCAAF | 2019/10/26 19:30 | Oklahoma State v Iowa State | L | 34-27 |
| NCAAF | 2019/10/19 16:00 | Iowa State v Texas Tech | W | 34-24 |
| NCAAF | 2019/10/12 20:00 | Iowa State v West Virginia | W | 38-14 |
| NCAAF | 2019/10/05 18:00 | TCU v Iowa State | W | 24-49 |
| NCAAF | 2019/09/28 19:30 | Iowa State v Baylor | L | 21-23 |
| NCAAF | 2019/09/21 16:00 | UL Monroe v Iowa State | W | 20-72 |
| NCAAF | 2019/09/14 20:00 | Iowa v Iowa State | L | 18-17 |
| NCAAF | 2019/08/31 16:00 | Northern Iowa v Iowa State | W | 26-29 |
Away History
| NCAAF | 2019/10/26 16:00 | Oklahoma v Kansas State | L | 41-48 |
| NCAAF | 2019/10/19 16:00 | West Virginia v Oklahoma | W | 14-52 |
| NCAAF | 2019/10/12 16:00 | Oklahoma v Texas | W | 34-27 |
| NCAAF | 2019/10/05 16:30 | Oklahoma v Kansas | W | 45-20 |
| NCAAF | 2019/09/28 16:00 | Texas Tech v Oklahoma | W | 16-55 |
| NCAAF | 2019/09/15 00:00 | Oklahoma v UCLA | W | 48-14 |
| NCAAF | 2019/09/07 23:00 | South Dakota v Oklahoma | W | 14-70 |
| NCAAF | 2019/09/01 23:30 | Houston v Oklahoma | W | 31-49 |