Syracuse 34-56 Louisville 2019-11-23 21:00
Stadium: L&N Federal Credit Union Stadium Round: 1
Home Manager: Scott Satterfield Away Manager: Dino Babers
Head to Head
| NCAAF | 2018/11/10 00:00 | Louisville v Syracuse | W | 23-54 |
| NCAAF | 2017/11/18 20:30 | Syracuse v Louisville | L | 10-56 |
| NCAAF | 2016/09/10 00:00 | Louisville v Syracuse | L | 62-28 |
| NCAAF | 2015/11/07 17:30 | Louisville v Syracuse | L | 41-17 |
| NCAAF | 2014/10/03 23:00 | Syracuse v Louisville | L | 6-28 |
| NCAAF | 2012/11/10 12:00 | Syracuse v Louisville | W | 45-26 |
| NCAAF | 2011/10/29 12:00 | Louisville v Syracuse | L | 27-10 |
| NCAAF | 2010/11/06 12:00 | Syracuse v Louisville | L | 20-28 |
Home History
| NCAAF | 2019/11/16 21:00 | Syracuse v Duke | W | 49-6 |
| NCAAF | 2019/11/02 16:00 | Boston College v Syracuse | L | 58-27 |
| NCAAF | 2019/10/26 19:30 | Syracuse v Florida State | L | 17-35 |
| NCAAF | 2019/10/18 23:00 | Pittsburgh v Syracuse | L | 27-20 |
| NCAAF | 2019/10/11 00:00 | Syracuse v NC State | L | 10-16 |
| NCAAF | 2019/09/28 16:00 | Holy Cross v Syracuse | W | 3-41 |
| NCAAF | 2019/09/21 16:00 | Western Michigan v Syracuse | W | 33-52 |
| NCAAF | 2019/09/14 23:30 | Clemson v Syracuse | L | 41-6 |
Away History
| NCAAF | 2019/11/17 00:30 | Louisville v NC State | W | 34-20 |
| NCAAF | 2019/11/09 20:30 | Louisville v Miami Florida | L | 27-52 |
| NCAAF | 2019/10/26 19:30 | Virginia v Louisville | W | 21-28 |
| NCAAF | 2019/10/19 16:00 | Clemson v Louisville | L | 45-10 |
| NCAAF | 2019/10/12 23:30 | Louisville v Wake Forest | W | 62-59 |
| NCAAF | 2019/10/05 16:30 | Boston College v Louisville | W | 39-41 |
| NCAAF | 2019/09/21 19:30 | Louisville v Florida State | L | 24-35 |
| NCAAF | 2019/09/14 20:00 | Western Kentucky v Louisville | W | 21-38 |