[48] Southern Mississippi 30-45 Louisiana Tech [22] 2019-10-19 19:30
Stadium: Joe Aillet Stadium Round: 1
Home Manager: Skip Holtz Away Manager: Jay Hopson
Head to Head
| NCAAF | 2018/11/17 20:30 | Louisiana Tech v Southern Mississippi | W | 20-21 |
| NCAAF | 2017/10/21 23:00 | Southern Mississippi v Louisiana Tech | W | 34-27 |
| NCAAF | 2016/11/25 21:00 | Louisiana Tech v Southern Mississippi | W | 24-39 |
| NCAAF | 2015/11/28 17:00 | Louisiana Tech v Southern Mississippi | W | 24-58 |
| NCAAF | 2014/10/25 19:30 | Southern Mississippi v Louisiana Tech | L | 20-31 |
| NCAAF | 2011/09/03 12:00 | Southern Mississippi v Louisiana Tech | W | 19-17 |
| NCAAF | 2010/09/25 12:00 | Louisiana Tech v Southern Mississippi | W | 12-13 |
Home History
| NCAAF | 2019/10/12 23:00 | North Texas v Southern Mississippi | W | 27-45 |
| NCAAF | 2019/09/28 23:00 | UTEP v Southern Mississippi | W | 13-31 |
| NCAAF | 2019/09/21 16:00 | Southern Mississippi v Alabama | L | 7-49 |
| NCAAF | 2019/09/14 22:00 | Southern Mississippi v Troy | W | 47-42 |
| NCAAF | 2019/09/07 19:30 | Southern Mississippi v Mississippi State | L | 15-38 |
| NCAAF | 2019/08/31 23:00 | Alcorn State v Southern Mississippi | W | 10-38 |
| NCAAF | 2018/11/24 20:00 | Southern Mississippi v UTEP | W | 39-7 |
| NCAAF | 2018/11/17 20:30 | Louisiana Tech v Southern Mississippi | W | 20-21 |
Away History
| NCAAF | 2019/10/12 23:00 | Massachusetts v Louisiana Tech | W | 21-69 |
| NCAAF | 2019/09/28 23:00 | Louisiana Tech v Rice | W | 23-20 |
| NCAAF | 2019/09/21 00:00 | Florida Intl v Louisiana Tech | W | 31-43 |
| NCAAF | 2019/09/14 21:00 | Louisiana Tech v Bowling Green | W | 35-7 |
| NCAAF | 2019/09/07 19:30 | Grambling State v Louisiana Tech | W | 14-20 |
| NCAAF | 2019/09/01 00:00 | Louisiana Tech v Texas | L | 14-45 |
| NCAAF | 2018/12/23 03:30 | Louisiana Tech v Hawaii | W | 31-14 |
| NCAAF | 2018/11/24 17:00 | Western Kentucky v Louisiana Tech | L | 30-15 |