[83] Michigan State 10-44 Michigan [27] 2019-11-16 17:00
Stadium: Michigan Stadium Round: 1
Home Manager: Jim Harbaugh Away Manager: Mark Dantonio
Head to Head
| NCAAF | 2018/10/20 16:00 | Michigan v Michigan State | L | 21-7 |
| NCAAF | 2017/10/07 23:30 | Michigan State v Michigan | W | 14-10 |
| NCAAF | 2016/10/29 16:00 | Michigan v Michigan State | L | 32-23 |
| NCAAF | 2015/10/17 19:30 | Michigan v Michigan State | W | 23-27 |
| NCAAF | 2014/10/25 19:30 | Michigan State v Michigan | W | 35-11 |
| NCAAF | 2012/10/20 12:00 | Michigan v Michigan State | L | 12-10 |
| NCAAF | 2011/10/15 12:00 | Michigan State v Michigan | W | 28-14 |
| NCAAF | 2010/10/09 12:00 | Michigan v Michigan State | W | 17-34 |
Home History
| NCAAF | 2019/11/09 20:30 | Illinois v Michigan State | L | 37-34 |
| NCAAF | 2019/10/26 19:30 | Penn State v Michigan State | L | 28-7 |
| NCAAF | 2019/10/12 19:30 | Michigan State v Wisconsin | L | 0-38 |
| NCAAF | 2019/10/05 23:30 | Michigan State v Ohio State | L | 10-34 |
| NCAAF | 2019/09/28 19:30 | Indiana v Michigan State | W | 31-40 |
| NCAAF | 2019/09/21 16:00 | Michigan State v Northwestern | W | 31-10 |
| NCAAF | 2019/09/14 20:00 | Arizona State v Michigan State | L | 10-7 |
| NCAAF | 2019/09/07 23:30 | Western Michigan v Michigan State | W | 17-51 |
Away History
| NCAAF | 2019/11/02 16:00 | Michigan v Maryland | W | 38-7 |
| NCAAF | 2019/10/26 23:30 | Notre Dame v Michigan | W | 14-45 |
| NCAAF | 2019/10/19 23:30 | Michigan v Penn State | L | 21-28 |
| NCAAF | 2019/10/12 16:00 | Michigan v Illinois | W | 42-25 |
| NCAAF | 2019/10/05 16:00 | Iowa v Michigan | W | 3-10 |
| NCAAF | 2019/09/28 16:00 | Rutgers v Michigan | W | 0-52 |
| NCAAF | 2019/09/21 16:00 | Michigan v Wisconsin | L | 14-35 |
| NCAAF | 2019/09/07 16:00 | Army v Michigan | W | 21-24 |