Home History
| NCAAF | 2010/11/27 12:00 | Purdue v Indiana | L | 31-34 |
| NCAAF | 2010/11/20 12:00 | Michigan State v Purdue | L | 35-31 |
| NCAAF | 2010/11/13 12:00 | Purdue v Michigan | L | 16-27 |
| NCAAF | 2010/11/06 12:00 | Purdue v Wisconsin | L | 13-34 |
| NCAAF | 2010/10/30 12:00 | Illinois v Purdue | L | 44-10 |
| NCAAF | 2010/10/23 12:00 | Ohio State v Purdue | L | 49-0 |
| NCAAF | 2010/10/16 12:00 | Purdue v Minnesota | W | 28-17 |
| NCAAF | 2010/10/09 12:00 | Northwestern v Purdue | W | 17-20 |
Away History
| NCAAF | 2010/12/04 12:00 | Florida Intl v Middle Tennessee St. | W | 27-28 |
| NCAAF | 2010/11/27 12:00 | Middle Tennessee St. v Florida Atlantic | W | 38-14 |
| NCAAF | 2010/11/20 12:00 | Western Kentucky v Middle Tennessee St. | W | 26-27 |
| NCAAF | 2010/11/13 12:00 | Middle Tennessee St. v North Texas | L | 17-23 |
| NCAAF | 2010/11/02 12:00 | Arkansas State v Middle Tennessee St. | L | 51-24 |
| NCAAF | 2010/10/23 12:00 | Middle Tennessee St. v UL Monroe | W | 38-10 |
| NCAAF | 2010/10/16 12:00 | Georgia Tech v Middle Tennessee St. | L | 42-14 |
| NCAAF | 2010/10/05 12:00 | Middle Tennessee St. v Troy | L | 13-42 |