Head to Head
| NCAAF | 2011/11/05 12:00 | East Carolina v Southern Mississippi | W | 28-48 |
| NCAAF | 2010/10/09 12:00 | Southern Mississippi v East Carolina | L | 43-44 |
| NCAAF | 2009/11/28 12:00 | East Carolina v Southern Mississippi | L | 25-20 |
| NCAAF | 2008/11/15 12:00 | Southern Mississippi v East Carolina | W | 21-3 |
| NCAAF | 2007/09/15 12:00 | East Carolina v Southern Mississippi | W | 21-28 |
| NCAAF | 2006/10/28 12:00 | Southern Mississippi v East Carolina | L | 17-20 |
| NCAAF | 2005/10/01 12:00 | East Carolina v Southern Mississippi | W | 7-33 |
| NCAAF | 2004/10/23 12:00 | Southern Mississippi v East Carolina | W | 51-10 |
Home History
| NCAAF | 2012/09/01 12:00 | Nebraska v Southern Mississippi | L | 49-20 |
| NCAAF | 2011/12/03 12:00 | Houston v Southern Mississippi | W | 28-49 |
| NCAAF | 2011/11/26 12:00 | Southern Mississippi v Memphis | W | 44-7 |
| NCAAF | 2011/11/17 12:00 | UAB v Southern Mississippi | L | 34-31 |
| NCAAF | 2011/11/12 12:00 | Southern Mississippi v Central Florida | W | 30-29 |
| NCAAF | 2011/11/05 12:00 | East Carolina v Southern Mississippi | W | 28-48 |
| NCAAF | 2011/10/29 12:00 | UTEP v Southern Mississippi | W | 13-31 |
| NCAAF | 2011/10/22 12:00 | Southern Mississippi v SMU | W | 27-3 |
Away History
| NCAAF | 2012/09/08 12:00 | South Carolina v East Carolina | L | 48-10 |
| NCAAF | 2012/09/01 12:00 | East Carolina v Appalachian St | W | 35-13 |
| NCAAF | 2011/11/26 12:00 | Marshall v East Carolina | L | 34-27 |
| NCAAF | 2011/11/19 12:00 | East Carolina v Central Florida | W | 38-31 |
| NCAAF | 2011/11/12 12:00 | UTEP v East Carolina | L | 22-17 |
| NCAAF | 2011/11/05 12:00 | East Carolina v Southern Mississippi | L | 28-48 |
| NCAAF | 2011/10/29 12:00 | East Carolina v Tulane | W | 34-13 |
| NCAAF | 2011/10/22 12:00 | Navy v East Carolina | W | 35-38 |