Head to Head
| NCAAF | 2009/10/17 12:00 | Notre Dame v USC | W | 27-34 |
| NCAAF | 2008/11/29 12:00 | USC v Notre Dame | W | 38-3 |
| NCAAF | 2007/10/20 12:00 | Notre Dame v USC | W | 0-38 |
| NCAAF | 2006/11/25 12:00 | USC v Notre Dame | W | 44-24 |
| NCAAF | 2005/10/15 12:00 | Notre Dame v USC | W | 31-34 |
| NCAAF | 2004/11/27 12:00 | USC v Notre Dame | W | 41-10 |
| NCAAF | 2003/10/18 12:00 | Notre Dame v USC | W | 14-45 |
| NCAAF | 2002/11/30 12:00 | USC v Notre Dame | W | 44-13 |
Home History
| NCAAF | 2010/11/20 12:00 | Oregon State v USC | L | 36-7 |
| NCAAF | 2010/11/13 12:00 | Arizona v USC | W | 21-24 |
| NCAAF | 2010/11/06 12:00 | USC v Arizona State | W | 34-33 |
| NCAAF | 2010/10/30 12:00 | USC v Oregon | L | 32-53 |
| NCAAF | 2010/10/16 12:00 | USC v California | W | 48-14 |
| NCAAF | 2010/10/09 12:00 | Stanford v USC | L | 37-35 |
| NCAAF | 2010/10/02 12:00 | USC v Washington | L | 31-32 |
| NCAAF | 2010/09/25 12:00 | Washington State v USC | W | 16-50 |
Away History
| NCAAF | 2010/11/20 12:00 | Army v Notre Dame | W | 3-27 |
| NCAAF | 2010/11/13 12:00 | Notre Dame v Utah | W | 28-3 |
| NCAAF | 2010/10/30 12:00 | Notre Dame v Tulsa | L | 27-28 |
| NCAAF | 2010/10/23 12:00 | Navy v Notre Dame | L | 35-17 |
| NCAAF | 2010/10/16 12:00 | Notre Dame v Western Michigan | W | 44-20 |
| NCAAF | 2010/10/09 12:00 | Notre Dame v Pittsburgh | W | 23-17 |
| NCAAF | 2010/10/02 12:00 | Boston College v Notre Dame | W | 13-31 |
| NCAAF | 2010/09/25 12:00 | Notre Dame v Stanford | L | 14-37 |