Home History
| NCAAF | 2010/10/23 12:00 | Miami Ohio v Ohio | W | 13-34 |
| NCAAF | 2010/10/16 12:00 | Ohio v Akron | W | 38-10 |
| NCAAF | 2010/10/09 12:00 | Ohio v Bowling Green | W | 49-25 |
| NCAAF | 2010/10/02 12:00 | Eastern Michigan v Ohio | W | 17-30 |
| NCAAF | 2010/09/25 12:00 | Marshall v Ohio | L | 24-23 |
| NCAAF | 2010/09/18 12:00 | Ohio State v Ohio | L | 43-7 |
| NCAAF | 2010/09/11 12:00 | Ohio v Toledo | L | 13-20 |
| NCAAF | 2010/09/04 12:00 | Ohio v Wofford | W | 33-10 |
Away History
| NCAAF | 2010/10/23 12:00 | Lafayette v Western Kentucky | L | 21-54 |
| NCAAF | 2010/10/16 12:00 | Troy v Lafayette | L | 31-24 |
| NCAAF | 2010/10/08 12:00 | Lafayette v Oklahoma State | L | 28-54 |
| NCAAF | 2010/10/02 12:00 | North Texas v Lafayette | W | 27-28 |
| NCAAF | 2010/09/25 12:00 | Lafayette v Middle Tennessee St. | L | 14-34 |
| NCAAF | 2010/09/11 12:00 | Lafayette v Arkansas State | W | 31-24 |
| NCAAF | 2010/09/04 12:00 | Georgia v Lafayette | L | 55-7 |
| NCAAF | 2009/11/28 12:00 | Lafayette v Troy | L | 31-48 |