Home History
| NCAAF | 2000/11/11 12:00 | Michigan State v Purdue | L | 30-10 |
| NCAAF | 2000/10/28 12:00 | Purdue v Ohio State | W | 31-27 |
| NCAAF | 2000/10/21 12:00 | Wisconsin v Purdue | W | 24-30 |
| NCAAF | 2000/10/14 12:00 | Northwestern v Purdue | W | 28-41 |
| NCAAF | 2000/10/07 12:00 | Purdue v Michigan | W | 32-31 |
| NCAAF | 2000/09/30 12:00 | Penn State v Purdue | L | 22-20 |
| NCAAF | 2000/09/23 12:00 | Purdue v Minnesota | W | 38-24 |
| NCAAF | 2000/09/16 12:00 | Notre Dame v Purdue | L | 23-21 |
Away History
| NCAAF | 2000/11/11 12:00 | Indiana v Wisconsin | L | 22-43 |
| NCAAF | 2000/11/04 12:00 | Illinois v Indiana | L | 42-35 |
| NCAAF | 2000/10/28 12:00 | Indiana v Penn State | L | 24-27 |
| NCAAF | 2000/10/21 12:00 | Indiana v Minnesota | W | 51-43 |
| NCAAF | 2000/10/14 12:00 | Michigan v Indiana | L | 58-0 |
| NCAAF | 2000/10/07 12:00 | Northwestern v Indiana | L | 52-33 |
| NCAAF | 2000/09/30 12:00 | Indiana v Iowa | W | 45-33 |
| NCAAF | 2000/09/23 12:00 | Indiana v Cincinnati | W | 42-6 |