Home History
| NCAAF | 2000/11/11 12:00 | Middle Tennessee St. v South Florida | W | 45-9 |
| NCAAF | 2000/11/04 12:00 | Connecticut v Middle Tennessee St. | W | 10-66 |
| NCAAF | 2000/10/28 12:00 | Mississippi State v Middle Tennessee St. | L | 61-35 |
| NCAAF | 2000/10/21 12:00 | UAB v Middle Tennessee St. | L | 14-9 |
| NCAAF | 2000/10/14 12:00 | Middle Tennessee St. v UL Monroe | W | 28-0 |
| NCAAF | 2000/10/07 12:00 | Middle Tennessee St. v Louisiana Tech | W | 49-21 |
| NCAAF | 2000/09/23 12:00 | Maryland v Middle Tennessee St. | L | 45-27 |
| NCAAF | 2000/09/16 12:00 | Middle Tennessee St. v Murray State | W | 44-28 |
Away History
| NCAAF | 2000/11/11 12:00 | Lafayette v Jacksonville State | L | 14-28 |
| NCAAF | 2000/11/04 12:00 | UL Monroe v Lafayette | W | 18-21 |
| NCAAF | 2000/10/28 12:00 | Lafayette v North Texas | L | 0-13 |
| NCAAF | 2000/10/14 12:00 | Louisiana Tech v Lafayette | L | 48-14 |
| NCAAF | 2000/10/07 12:00 | Lafayette v Tulane | L | 37-38 |
| NCAAF | 2000/09/30 12:00 | UAB v Lafayette | L | 47-2 |
| NCAAF | 2000/09/23 12:00 | Lafayette v Northwestern State | L | 21-23 |
| NCAAF | 2000/09/16 12:00 | Texas Tech v Lafayette | L | 26-0 |