Home History
| NCAAF | 2000/11/04 12:00 | Wake Forest v Duke | W | 28-26 |
| NCAAF | 2000/10/21 12:00 | Maryland v Wake Forest | L | 37-7 |
| NCAAF | 2000/10/14 12:00 | Georgia Tech v Wake Forest | L | 52-20 |
| NCAAF | 2000/10/07 12:00 | Wake Forest v Vanderbilt | L | 10-17 |
| NCAAF | 2000/09/30 12:00 | Wake Forest v Virginia | L | 10-27 |
| NCAAF | 2000/09/16 12:00 | Clemson v Wake Forest | L | 55-7 |
| NCAAF | 2000/09/09 12:00 | Wake Forest v North Carolina | L | 14-35 |
| NCAAF | 2000/08/31 12:00 | Wake Forest v Appalachian St | L | 16-20 |
Away History
| NCAAF | 2000/11/04 12:00 | Florida State v Clemson | W | 54-7 |
| NCAAF | 2000/10/28 12:00 | NC State v Florida State | W | 14-58 |
| NCAAF | 2000/10/21 12:00 | Florida State v Virginia | W | 37-3 |
| NCAAF | 2000/10/14 12:00 | Florida State v Duke | W | 63-14 |
| NCAAF | 2000/10/07 12:00 | Miami Florida v Florida State | L | 27-24 |
| NCAAF | 2000/09/28 12:00 | Maryland v Florida State | W | 7-59 |
| NCAAF | 2000/09/23 12:00 | Florida State v Louisville | W | 31-0 |
| NCAAF | 2000/09/16 12:00 | Florida State v North Carolina | W | 63-14 |