Home History
| NCAAF | 2000/10/21 12:00 | Michigan v Michigan State | L | 14-0 |
| NCAAF | 2000/10/14 12:00 | Michigan State v Wisconsin | L | 10-17 |
| NCAAF | 2000/10/07 12:00 | Iowa v Michigan State | L | 21-16 |
| NCAAF | 2000/09/30 12:00 | Michigan State v Northwestern | L | 17-37 |
| NCAAF | 2000/09/23 12:00 | Michigan State v Notre Dame | W | 27-21 |
| NCAAF | 2000/09/16 12:00 | Missouri v Michigan State | W | 10-13 |
| NCAAF | 2000/09/09 12:00 | Michigan State v Marshall | W | 34-24 |
Away History
| NCAAF | 2000/10/21 12:00 | Penn State v Illinois | L | 39-25 |
| NCAAF | 2000/10/14 12:00 | Illinois v Iowa | W | 31-0 |
| NCAAF | 2000/09/30 12:00 | Minnesota v Illinois | L | 44-10 |
| NCAAF | 2000/09/23 12:00 | Illinois v Michigan | L | 31-35 |
| NCAAF | 2000/09/16 12:00 | Illinois v California | W | 17-15 |
| NCAAF | 2000/09/09 12:00 | San Diego State v Illinois | W | 13-49 |
| NCAAF | 2000/09/02 12:00 | Illinois v Middle Tennessee St. | W | 35-6 |