Mississippi State 61-35 Middle Tennessee St. 2000-10-28 12:00
Home History
| NCAAF | 2000/10/21 12:00 | LSU v Mississippi State | L | 45-38 |
| NCAAF | 2000/10/07 12:00 | Mississippi State v Auburn | W | 17-10 |
| NCAAF | 2000/09/30 12:00 | Mississippi State v Florida | W | 47-35 |
| NCAAF | 2000/09/23 12:00 | South Carolina v Mississippi State | L | 23-19 |
| NCAAF | 2000/09/14 12:00 | BYU v Mississippi State | W | 28-44 |
| NCAAF | 2000/09/02 12:00 | Memphis v Mississippi State | W | 3-17 |
Away History
| NCAAF | 2000/10/21 12:00 | UAB v Middle Tennessee St. | L | 14-9 |
| NCAAF | 2000/10/14 12:00 | Middle Tennessee St. v UL Monroe | W | 28-0 |
| NCAAF | 2000/10/07 12:00 | Middle Tennessee St. v Louisiana Tech | W | 49-21 |
| NCAAF | 2000/09/23 12:00 | Maryland v Middle Tennessee St. | L | 45-27 |
| NCAAF | 2000/09/16 12:00 | Middle Tennessee St. v Murray State | W | 44-28 |
| NCAAF | 2000/09/09 12:00 | Florida v Middle Tennessee St. | L | 55-0 |
| NCAAF | 2000/09/02 12:00 | Illinois v Middle Tennessee St. | L | 35-6 |