Head to Head
| NCAAF | 2008/11/15 12:00 | Clemson v Duke | L | 31-7 |
| NCAAF | 2007/11/03 12:00 | Duke v Clemson | L | 10-47 |
| NCAAF | 2005/11/05 12:00 | Clemson v Duke | L | 49-20 |
| NCAAF | 2004/11/13 12:00 | Duke v Clemson | W | 16-13 |
| NCAAF | 2003/11/15 12:00 | Clemson v Duke | L | 40-7 |
| NCAAF | 2002/11/02 12:00 | Duke v Clemson | L | 31-34 |
| NCAAF | 2001/12/01 12:00 | Clemson v Duke | L | 59-31 |
| NCAAF | 2000/09/30 12:00 | Duke v Clemson | L | 22-52 |
Home History
| NCAAF | 2012/10/27 12:00 | Florida State v Duke | L | 48-7 |
| NCAAF | 2012/10/20 12:00 | Duke v North Carolina | W | 33-30 |
| NCAAF | 2012/10/13 12:00 | Virginia Tech v Duke | L | 41-20 |
| NCAAF | 2012/10/06 12:00 | Duke v Virginia | W | 42-17 |
| NCAAF | 2012/09/29 12:00 | Wake Forest v Duke | W | 27-34 |
| NCAAF | 2012/09/22 12:00 | Duke v Memphis | W | 38-14 |
| NCAAF | 2012/09/15 12:00 | Duke v North Carolina Central | W | 54-17 |
| NCAAF | 2012/09/08 12:00 | Stanford v Duke | L | 50-13 |
Away History
| NCAAF | 2012/10/25 12:00 | Wake Forest v Clemson | W | 13-42 |
| NCAAF | 2012/10/20 12:00 | Clemson v Virginia Tech | W | 38-17 |
| NCAAF | 2012/10/06 12:00 | Clemson v Georgia Tech | W | 47-31 |
| NCAAF | 2012/09/29 12:00 | Boston College v Clemson | W | 31-45 |
| NCAAF | 2012/09/22 12:00 | Florida State v Clemson | L | 49-37 |
| NCAAF | 2012/09/15 12:00 | Clemson v Furman | W | 41-7 |
| NCAAF | 2012/09/08 12:00 | Clemson v Ball State | W | 52-27 |
| NCAAF | 2012/09/01 12:00 | Auburn v Clemson | W | 19-26 |