Head to Head
| NCAAF | 2002/11/14 12:00 | Southern Mississippi v Louisville | W | 17-20 |
| NCAAF | 2001/10/16 12:00 | Louisville v Southern Mississippi | W | 24-14 |
| NCAAF | 2000/11/04 12:00 | Southern Mississippi v Louisville | W | 28-49 |
Home History
| NCAAF | 2009/09/26 12:00 | Utah v Louisville | L | 30-14 |
| NCAAF | 2009/09/19 12:00 | Kentucky v Louisville | L | 31-27 |
| NCAAF | 2009/09/05 12:00 | Louisville v Indiana State | W | 30-10 |
| NCAAF | 2008/12/04 12:00 | Rutgers v Louisville | L | 63-14 |
| NCAAF | 2008/11/22 12:00 | Louisville v West Virginia | L | 21-35 |
| NCAAF | 2008/11/14 12:00 | Louisville v Cincinnati | L | 20-28 |
| NCAAF | 2008/11/08 12:00 | Pittsburgh v Louisville | L | 41-7 |
| NCAAF | 2008/11/01 12:00 | Syracuse v Louisville | L | 28-21 |
Away History
| NCAAF | 2009/10/01 12:00 | UAB v Southern Mississippi | L | 30-17 |
| NCAAF | 2009/09/26 12:00 | Kansas v Southern Mississippi | L | 35-28 |
| NCAAF | 2009/09/19 12:00 | Southern Mississippi v Virginia | W | 37-34 |
| NCAAF | 2009/09/12 12:00 | Southern Mississippi v Central Florida | W | 26-19 |
| NCAAF | 2009/09/05 12:00 | Southern Mississippi v Alcorn State | W | 52-0 |
| NCAAF Bowl Games | 2008/12/21 12:00 | Southern Mississippi v Troy | W | 30-27 |
| NCAAF | 2008/11/29 12:00 | SMU v Southern Mississippi | W | 12-28 |
| NCAAF | 2008/11/15 12:00 | Southern Mississippi v East Carolina | W | 21-3 |