Home History
| NCAAF | 2000/10/28 12:00 | East Carolina v UAB | L | 13-16 |
| NCAAF | 2000/10/19 12:00 | Louisville v East Carolina | W | 25-28 |
| NCAAF | 2000/10/14 12:00 | East Carolina v Army | W | 42-21 |
| NCAAF | 2000/10/07 12:00 | Memphis v East Carolina | L | 17-10 |
| NCAAF | 2000/09/23 12:00 | East Carolina v Syracuse | W | 34-17 |
| NCAAF | 2000/09/16 12:00 | East Carolina v Tulane | W | 37-17 |
| NCAAF | 2000/09/07 12:00 | East Carolina v Virginia Tech | L | 28-45 |
| NCAAF | 2000/09/02 12:00 | Duke v East Carolina | W | 0-38 |
Away History
| NCAAF | 2000/11/04 12:00 | Tulane v Houston | L | 41-23 |
| NCAAF | 2000/10/28 12:00 | Houston v Southern Mississippi | L | 3-6 |
| NCAAF | 2000/10/21 12:00 | Memphis v Houston | W | 30-33 |
| NCAAF | 2000/10/07 12:00 | Cincinnati v Houston | L | 48-31 |
| NCAAF | 2000/09/30 12:00 | Houston v SMU | W | 17-15 |
| NCAAF | 2000/09/23 12:00 | Texas v Houston | L | 48-0 |
| NCAAF | 2000/09/16 12:00 | Houston v Army | W | 31-30 |
| NCAAF | 2000/09/09 12:00 | LSU v Houston | L | 28-13 |