[22] BUF Sabres 5-2 FLA Panthers [9] 2019-11-24 22:00
Stadium: Amerant Bank Arena
Home Manager: Joel Quenneville Away Manager: Ralph Krueger
Head to Head
| NHL | 2019/10/11 23:00 | FLA Panthers v BUF Sabres | W | 2-3 |
| NHL | 2019/02/20 00:00 | BUF Sabres v FLA Panthers | L | 2-4 |
| NHL | 2019/01/04 00:00 | FLA Panthers v BUF Sabres | W | 3-4 |
| NHL | 2018/12/19 00:00 | FLA Panthers v BUF Sabres | L | 5-2 |
| NHL | 2018/12/01 00:00 | BUF Sabres v FLA Panthers | L | 2-3 |
| NHL | 2018/04/07 23:00 | BUF Sabres v FLA Panthers | L | 3-4 |
| NHL | 2018/03/03 00:30 | BUF Sabres v FLA Panthers | L | 1-4 |
| NHL | 2018/02/02 00:00 | FLA Panthers v BUF Sabres | L | 4-2 |
Home History
| NHL | 2019/11/22 00:00 | BUF Sabres v BOS Bruins | L | 2-3 |
| NHL | 2019/11/20 00:00 | MIN Wild v BUF Sabres | L | 4-1 |
| NHL | 2019/11/18 00:00 | BUF Sabres v CHI Blackhawks | L | 1-4 |
| NHL | 2019/11/17 00:00 | OTT Senators v BUF Sabres | W | 2-4 |
| NHL | 2019/11/15 00:00 | CAR Hurricanes v BUF Sabres | L | 5-4 |
| NHL | 2019/11/09 18:00 | BUF Sabres v TB Lightning | L | 3-5 |
| NHL | 2019/11/08 19:00 | TB Lightning v BUF Sabres | L | 3-2 |
| NHL | 2019/11/02 23:00 | NY Islanders v BUF Sabres | L | 1-0 |
Away History
| NHL | 2019/11/24 00:00 | FLA Panthers v CAR Hurricanes | L | 2-4 |
| NHL | 2019/11/22 00:00 | ANA Ducks v FLA Panthers | W | 4-5 |
| NHL | 2019/11/20 00:00 | PHI Flyers v FLA Panthers | W | 2-5 |
| NHL | 2019/11/17 00:00 | NY Rangers v FLA Panthers | W | 3-4 |
| NHL | 2019/11/15 00:00 | WIN Jets v FLA Panthers | L | 4-3 |
| NHL | 2019/11/13 00:00 | FLA Panthers v BOS Bruins | W | 5-4 |
| NHL | 2019/11/10 18:00 | FLA Panthers v NY Rangers | W | 6-5 |
| NHL | 2019/11/09 18:00 | FLA Panthers v NY Islanders | L | 1-2 |