Stadium: Blackstock Stadium Round: 1
| NCAAF | 2019/09/21 16:00 | Kenyon Lords v Depauw Tigers | W | 7-21 |
| NCAAF | 2019/09/14 18:00 | Central Dutch v Depauw Tigers | L | 45-19 |
| NCAAF | 2018/11/10 18:07 | Wabash Little Giants v Depauw Tigers | L | 24-17 |
| NCAAF | 2018/11/03 17:00 | Depauw Tigers v Kenyon Lords | W | 38-6 |
| NCAAF | 2018/10/27 17:00 | Allegheny Gators v Depauw Tigers | L | 20-19 |
| NCAAF | 2018/10/20 17:00 | Wittenberg Tigers v Depauw Tigers | L | 38-23 |
| NCAAF | 2018/10/13 17:00 | Depauw Tigers v Denison Big Red | L | 12-20 |
| NCAAF | 2018/10/06 17:00 | Oberlin Yeomen v Depauw Tigers | W | 26-28 |
| NCAAF | 2019/09/21 20:30 | Wittenberg Tigers v Wooster Scots | W | 14-12 |
| NCAAF | 2019/09/14 17:00 | Hiram Terriers v Wittenberg Tigers | W | 12-36 |
| NCAAF | 2019/09/07 17:00 | Washington And Jefferson Presidents v Wittenberg Tigers | L | 16-8 |
| NCAAF | 2018/11/10 18:00 | Wooster Scots v Wittenberg Tigers | W | 21-27 |
| NCAAF | 2018/11/03 17:00 | Ohio Wesleyan Battling Bishops v Wittenberg Tigers | W | 13-42 |
| NCAAF | 2018/10/27 17:00 | Wittenberg Tigers v Wabash Little Giants | L | 21-28 |
| NCAAF | 2018/10/20 17:00 | Wittenberg Tigers v Depauw Tigers | W | 38-23 |
| NCAAF | 2018/10/13 17:00 | Allegheny Gators v Wittenberg Tigers | W | 14-41 |