Stadium: Dwight T. Reed Stadium Round: 1
| NCAAF | 2019/09/05 23:00 | Washburn Ichabods Football v Blue Tigers | L | 49-27 |
| NCAAF | 2018/11/10 18:00 | Blue Tigers v McKendree | L | 32-50 |
| NCAAF | 2018/11/03 19:00 | Tarleton State v Blue Tigers | L | 59-3 |
| NCAAF | 2018/10/28 00:00 | Missouri S&t Miners v Blue Tigers | L | 45-7 |
| NCAAF | 2018/10/20 17:00 | William Jewell College Cardinals v Blue Tigers | W | 14-23 |
| NCAAF | 2018/10/13 19:00 | Truman Bulldogs v Blue Tigers | L | 20-13 |
| NCAAF | 2018/10/06 19:00 | Blue Tigers v Quincy | L | 13-14 |
| NCAAF | 2018/09/29 22:00 | Indianapolis Greyhounds v Blue Tigers | L | 41-17 |
| NCAAF | 2019/09/05 23:00 | Missouri Southern Lions v Nebraska Kearney | L | 27-39 |
| NCAAF | 2018/11/10 20:00 | Missouri Southern Lions v Pittsburgh State Gorillas | L | 0-41 |
| NCAAF | 2018/11/03 19:00 | Emporia State v Missouri Southern Lions | L | 48-0 |
| NCAAF | 2018/10/27 19:00 | Missouri Southern Lions v Central Oklahoma | L | 0-31 |
| NCAAF | 2018/10/20 22:00 | Missouri Southern Lions v Northeastern State Riverhawks | W | 24-19 |
| NCAAF | 2018/10/13 18:00 | Washburn Ichabods Football v Missouri Southern Lions | L | 63-7 |
| NCAAF | 2018/10/06 19:00 | Missouri Southern Lions v Missouri Western Griffons | L | 10-33 |
| NCAAF | 2018/09/29 18:00 | Central Missouri Mules v Missouri Southern Lions | L | 61-7 |