Stadium: Justin F. Coressel Stadium Round: 1
| NCAAF | 2019/10/05 17:30 | Mount St. Joseph Lions v Defiance Yellow Jackets | L | 59-6 |
| NCAAF | 2019/09/28 17:30 | Anderson Ravens v Defiance Yellow Jackets | L | 56-29 |
| NCAAF | 2019/09/19 23:00 | Manchester Spartans v Defiance Yellow Jackets | L | 52-21 |
| NCAAF | 2019/09/14 18:30 | Hope Flying Dutchmen v Defiance Yellow Jackets | L | 80-6 |
| NCAAF | 2019/09/07 22:00 | Albion Britons v Defiance Yellow Jackets | L | 56-6 |
| NCAAF | 2018/11/10 18:30 | Bluffton Beavers v Defiance Yellow Jackets | L | 34-7 |
| NCAAF | 2018/11/03 17:30 | Earlham Quakers v Defiance Yellow Jackets | W | 10-28 |
| NCAAF | 2018/10/27 17:30 | Defiance Yellow Jackets v Rose Hulman Engineers | L | 6-35 |
| NCAAF | 2019/10/05 17:30 | Hanover v Anderson Ravens | W | 70-0 |
| NCAAF | 2019/09/28 17:30 | Hanover v Bluffton Beavers | W | 28-10 |
| NCAAF | 2019/09/21 17:00 | Maryville Scots v Hanover | W | 10-31 |
| NCAAF | 2019/09/14 17:00 | Hanover v Adrian Bulldogs | W | 49-28 |
| NCAAF | 2019/09/07 17:30 | Hanover v Centre Colonels | L | 31-45 |
| NCAAF | 2018/11/17 18:00 | North Central Illinois v Hanover | L | 52-0 |
| NCAAF | 2018/11/10 18:30 | Franklin College Grizzlies v Hanover | W | 20-23 |
| NCAAF | 2018/11/03 18:00 | Hanover v Rose Hulman Engineers | W | 29-14 |