Head to Head
| England Premier League 2 | 2019/01/04 19:00 | Southampton U23 v Stoke U23 | W | 2-0 |
| England Premier League 2 | 2018/08/20 18:00 | Stoke U23 v Southampton U23 | W | 1-4 |
| England Premier League 2 | 2018/01/29 19:00 | Stoke U23 v Southampton U23 | W | 0-2 |
| England Premier League 2 | 2017/09/18 18:00 | Southampton U23 v Stoke U23 | W | 3-0 |
Home History
| England Premier League 2 | 2019/09/27 18:00 | Wolverhampton U23 v Southampton U23 | W | 1-2 |
| England Premier League 2 | 2019/09/21 14:00 | Southampton U23 v Chelsea U23 | L | 0-2 |
| England Premier League 2 | 2019/09/13 11:00 | Tottenham U23 v Southampton U23 | D | 2-2 |
| England Premier League 2 | 2019/08/30 18:00 | Everton U23 v Southampton U23 | L | 8-2 |
| England Premier League 2 | 2019/08/26 18:00 | Southampton U23 v Liverpool U23 | L | 2-4 |
| England Premier League 2 | 2019/08/19 18:00 | Southampton U23 v Derby U23 | L | 0-1 |
| England Premier League 2 | 2019/08/11 12:00 | Man City U23 v Southampton U23 | W | 3-4 |
| UK Friendlies | 2019/07/30 17:58 | Eastleigh v Southampton U23 | W | 0-1 |
Away History
| England Premier League 2 | 2019/09/30 18:00 | Reading U23 v Stoke U23 | W | 0-4 |
| England Premier League 2 | 2019/09/20 18:00 | Norwich U23 v Stoke U23 | W | 0-2 |
| England Premier League 2 | 2019/09/16 18:00 | Stoke U23 v Aston Villa U23 | W | 2-0 |
| England Premier League 2 | 2019/08/31 11:00 | Swansea U23 v Stoke U23 | W | 3-4 |
| England Premier League 2 | 2019/08/26 18:00 | Stoke U23 v Fulham U23 | L | 0-1 |
| England Premier League 2 | 2019/08/16 18:00 | Middlesbrough U23 v Stoke U23 | W | 0-2 |
| England Premier League 2 | 2019/08/12 18:00 | Stoke U23 v Sunderland U23 | D | 1-1 |
| Europe Friendlies | 2019/07/07 10:00 | Stoke U23 v Marseille | L | 0-1 |