[7] Northampton 22-20 Harlequins [6] 2017-05-06 15:00
Stadium: Franklin's Gardens Round: 22
Referee: JP Doyle Home Manager: Jim Mallinder Away Manager: Mark Mapletoft
Head to Head
| Premiership Rugby | 2016/10/08 14:00 | Harlequins v Northampton | L | 20-9 |
| Premiership Rugby | 2016/03/27 14:15 | Northampton v Harlequins | W | 29-23 |
| Premiership Rugby | 2016/02/06 14:00 | Harlequins v Northampton | W | 23-27 |
| Premiership Rugby | 2015/02/27 19:45 | Northampton v Harlequins | W | 17-13 |
| Premiership Rugby | 2014/12/27 16:30 | Harlequins v Northampton | W | 25-30 |
| European Rugby Challenge Cup | 2014/04/25 19:00 | Northampton v Harlequins | W | 18-10 |
Home History
| Premiership Rugby | 2017/04/29 14:00 | Exeter Chiefs v Northampton | L | 36-12 |
| Premiership Rugby | 2017/04/16 14:00 | Northampton v Saracens | L | 25-27 |
| Premiership Rugby | 2017/04/09 14:00 | Wasps v Northampton | L | 32-30 |
| Premiership Rugby | 2017/03/25 15:00 | Northampton v Leicester | L | 31-36 |
| Premiership Rugby | 2017/03/03 20:15 | Sale Sharks v Northampton | W | 12-32 |
| Premiership Rugby | 2017/02/25 15:00 | Northampton v Worcester Warriors | W | 24-14 |
| Premiership Rugby | 2017/02/19 15:00 | Newcastle Falcons v Northampton | L | 46-31 |
| Premiership Rugby | 2017/02/10 19:45 | Bath v Northampton | L | 32-30 |
Away History
| Premiership Rugby | 2017/04/28 18:45 | Harlequins v Wasps | W | 32-13 |
| Premiership Rugby | 2017/04/14 18:45 | Harlequins v Exeter Chiefs | L | 26-39 |
| Premiership Rugby Shield | 2017/04/10 18:30 | Bath United v Harlequins | L | 34-7 |
| Premiership Rugby | 2017/04/08 15:30 | Saracens v Harlequins | L | 40-19 |
| Premiership Rugby | 2017/03/25 15:00 | Harlequins v Newcastle Falcons | W | 53-17 |
| LV Cup | 2017/03/12 15:00 | Exeter Chiefs v Harlequins | L | 24-7 |
| Premiership Rugby | 2017/03/04 15:00 | Gloucester v Harlequins | W | 27-30 |
| Premiership Rugby | 2017/02/24 19:45 | Harlequins v Leicester | L | 18-27 |