Stadium: Joseph J. Gentile Center Round: 1
Home Manager: Porter Moser Away Manager: Bryan Mullins
| NCAAB | 2019/02/24 21:00 | Loyola Chicago v Southern Illinois | W | 53-63 |
| NCAAB | 2019/01/27 21:00 | Southern Illinois v Loyola Chicago | L | 50-75 |
| NCAAB | 2018/02/22 01:00 | Loyola Chicago v Southern Illinois | L | 75-56 |
| NCAAB | 2018/01/18 01:00 | Southern Illinois v Loyola Chicago | L | 65-79 |
| NCAAB | 2017/03/03 20:00 | Loyola Chicago v Southern Illinois | W | 50-55 |
| NCAAB | 2017/02/26 01:00 | Loyola Chicago v Southern Illinois | W | 70-72 |
| NCAAB | 2017/02/04 19:00 | Southern Illinois v Loyola Chicago | W | 67-61 |
| NCAAB | 2016/02/07 01:00 | Southern Illinois v Loyola Chicago | L | 59-73 |
| NCAAB | 2020/01/12 01:00 | Southern Illinois v Bradley | L | 48-67 |
| NCAAB | 2020/01/08 01:00 | Valparaiso v Southern Illinois | W | 50-63 |
| NCAAB | 2020/01/04 21:00 | Illinois St v Southern Illinois | W | 55-67 |
| NCAAB | 2019/12/31 01:00 | Southern Illinois v Indiana State | L | 56-68 |
| NCAAB | 2019/12/21 21:00 | SE Missouri State v Southern Illinois | W | 45-64 |
| NCAAB | 2019/12/19 01:00 | Hampton v Southern Illinois | W | 53-75 |
| NCAAB | 2019/12/15 21:00 | Southern Illinois v Missouri | L | 48-64 |
| NCAAB | 2019/12/07 20:00 | Southern Illinois v Southern Miss | L | 69-72 |
| NCAAB | 2020/01/11 21:00 | Evansville v Loyola Chicago | W | 44-78 |
| NCAAB | 2020/01/08 02:00 | Loyola Chicago v Drake | L | 62-65 |
| NCAAB | 2020/01/05 01:00 | Missouri State v Loyola Chicago | W | 58-62 |
| NCAAB | 2019/12/31 01:00 | Loyola Chicago v Valparaiso | W | 66-63 |
| NCAAB | 2019/12/22 20:00 | Davidson v Loyola Chicago | L | 59-56 |
| NCAAB | 2019/12/18 23:30 | Vanderbilt v Loyola Chicago | W | 70-78 |
| NCAAB | 2019/12/15 19:00 | Norfolk State v Loyola Chicago | W | 45-64 |
| NCAAB | 2019/12/07 19:00 | Quincy University v Loyola Chicago | W | 59-90 |