[22] FLA Panthers 2-4 BUF Sabres [24] 2017-03-27 23:00
Stadium: KeyBank Center Round: 1
Head to Head
| NHL | 2016/12/21 00:30 | BUF Sabres v FLA Panthers | W | 3-4 |
| NHL | 2016/10/29 16:53 | FLA Panthers v BUF Sabres | L | 0-3 |
Home History
| NHL | 2017/03/25 23:00 | CHI Blackhawks v FLA Panthers | W | 0-7 |
| NHL | 2017/03/23 23:30 | ARZ Coyotes v FLA Panthers | W | 1-3 |
| NHL | 2017/03/21 23:30 | CAR Hurricanes v FLA Panthers | L | 4-3 |
| NHL | 2017/03/19 17:00 | FLA Panthers v PIT Penguins | L | 0-4 |
| NHL | 2017/03/17 23:00 | FLA Panthers v NY Rangers | W | 4-3 |
| NHL | 2017/03/16 23:00 | FLA Panthers v CLB Blue Jackets | L | 1-2 |
| NHL | 2017/03/14 23:30 | TOR Maple Leafs v FLA Panthers | W | 2-7 |
| NHL | 2017/03/12 00:00 | FLA Panthers v TB Lightning | L | 2-3 |
Away History
| NHL | 2017/03/25 23:00 | TOR Maple Leafs v BUF Sabres | W | 2-5 |
| NHL | 2017/03/21 23:00 | PIT Penguins v BUF Sabres | L | 3-1 |
| NHL | 2017/03/20 23:30 | BUF Sabres v DET Red Wings | W | 2-1 |
| NHL | 2017/03/18 04:33 | BUF Sabres v ANA Ducks | D | 2-2 |
| NHL | 2017/03/18 02:00 | ANA Ducks v BUF Sabres | W | 1-2 |
| NHL | 2017/03/17 02:30 | BUF Sabres v LA Kings | L | 0-2 |
| NHL | 2017/03/15 02:30 | BUF Sabres v SJ Sharks | L | 1-4 |
| NHL | 2017/03/12 00:00 | CLB Blue Jackets v BUF Sabres | W | 3-5 |