[8] Spartak Moscow 2-1 Lokomotiv Moscow [3] 2020-08-23 16:00
Stadium: Otkritie Arena Round: 4
Referee: Sergey Gennadyevich Karasev Home Manager: Domenico Tedesco Away Manager: Marko Nikolic
Head to Head
| Russia Premier League | 2020/07/08 17:30 | Spartak Moscow v Lokomotiv Moscow | D | 1-1 |
| Europe Friendlies | 2020/02/05 15:00 | Spartak Moscow v Lokomotiv Moscow | L | 3-5 |
| Russia Premier League | 2019/10/27 13:30 | Lokomotiv Moscow v Spartak Moscow | W | 0-3 |
| Europe Friendlies | 2019/01/29 17:00 | Spartak Moscow v Lokomotiv Moscow | W | 4-0 |
| Russia Premier League | 2018/12/02 16:00 | Spartak Moscow v Lokomotiv Moscow | W | 2-1 |
| Russia Premier League | 2018/08/04 16:00 | Lokomotiv Moscow v Spartak Moscow | D | 0-0 |
| Russia Premier League | 2018/03/04 13:30 | Lokomotiv Moscow v Spartak Moscow | D | 0-0 |
| Russia Premier League | 2017/08/19 14:30 | Spartak Moscow v Lokomotiv Moscow | L | 3-4 |
Home History
| Russia Premier League | 2020/08/19 13:00 | FC Ufa v Spartak Moscow | D | 1-1 |
| Russia Premier League | 2020/08/14 17:00 | Spartak Moscow v FC Akhmat Grozny | W | 2-0 |
| Russia Premier League | 2020/08/09 17:00 | Spartak Moscow v PFC Sochi | D | 2-2 |
| Russia Premier League | 2020/07/22 16:00 | Rubin Kazan v Spartak Moscow | W | 1-2 |
| Russia Cup | 2020/07/19 15:30 | Zenit St Petersburg v Spartak Moscow | L | 2-1 |
| Russia Premier League | 2020/07/15 15:00 | Spartak Moscow v FC Akhmat Grozny | W | 3-0 |
| Russia Premier League | 2020/07/11 17:30 | PFC Sochi v Spartak Moscow | L | 1-0 |
| Russia Premier League | 2020/07/08 17:30 | Spartak Moscow v Lokomotiv Moscow | D | 1-1 |
Away History
| Russia Premier League | 2020/08/19 13:00 | Ural v Lokomotiv Moscow | D | 1-1 |
| Russia Premier League | 2020/08/15 16:00 | Lokomotiv Moscow v Krasnodar | W | 1-0 |
| Russia Premier League | 2020/08/11 17:00 | Rubin Kazan v Lokomotiv Moscow | W | 0-2 |
| Russia Super Cup | 2020/08/07 16:00 | Zenit St Petersburg v Lokomotiv Moscow | L | 2-1 |
| Russia Premier League | 2020/07/22 16:00 | Ural v Lokomotiv Moscow | W | 0-1 |
| Russia Premier League | 2020/07/16 17:30 | Lokomotiv Moscow v CSKA Moscow | W | 2-1 |
| Russia Premier League | 2020/07/12 13:30 | Lokomotiv Moscow v FC Ufa | D | 1-1 |
| Russia Premier League | 2020/07/08 17:30 | Spartak Moscow v Lokomotiv Moscow | D | 1-1 |