[14] Club Deportes Santa Cruz 2-4 Melipilla [7] 2020-08-31 19:00
Stadium: Estadio Municipal Joaquín Muñoz García Round: 5
Head to Head
| Chile Primera B | 2019/09/29 20:00 | Melipilla v Club Deportes Santa Cruz | D | 2-2 |
| Chile Primera B | 2019/05/18 22:00 | Club Deportes Santa Cruz v Melipilla | W | 1-0 |
| Chile Segunda | 2017/10/18 21:59 | Club Deportes Santa Cruz v Melipilla | W | 2-1 |
| Chile Segunda | 2017/08/16 22:02 | Melipilla v Club Deportes Santa Cruz | W | 2-3 |
| Chile Segunda | 2017/04/15 22:00 | Club Deportes Santa Cruz v Melipilla | W | 1-0 |
| Chile Segunda | 2017/01/14 22:02 | Melipilla v Club Deportes Santa Cruz | L | 3-0 |
Home History
| Chile Primera B | 2020/03/17 23:30 | Union San Felipe v Club Deportes Santa Cruz | D | 1-1 |
| Chile Primera B | 2020/03/01 21:00 | Club Deportes Santa Cruz v Rangers de Talca | L | 0-2 |
| Chile Primera B | 2020/02/23 22:00 | Deportes Valdivia v Club Deportes Santa Cruz | L | 1-0 |
| World Club Friendlies | 2020/02/15 22:59 | Club Deportes Santa Cruz v Colchagua CD | W | 4-0 |
| Chile Primera B | 2019/10/19 22:00 | Club Deportes Santa Cruz v Deportes Valdivia | D | 1-1 |
| Chile Primera B | 2019/10/13 20:00 | Union San Felipe v Club Deportes Santa Cruz | L | 3-0 |
| Chile Primera B | 2019/10/05 22:00 | Club Deportes Santa Cruz v Puerto Montt | W | 2-0 |
| Chile Primera B | 2019/09/29 20:00 | Melipilla v Club Deportes Santa Cruz | D | 2-2 |
Away History
| Chile Primera B | 2020/03/13 21:00 | Melipilla v Rangers de Talca | W | 1-0 |
| Chile Primera B | 2020/03/07 15:00 | San Marcos De Arica v Melipilla | L | 1-0 |
| Chile Primera B | 2020/03/03 23:30 | Melipilla v Deportes Valdivia | W | 2-0 |
| Chile Primera B | 2020/02/22 21:00 | Deportes Copiapo v Melipilla | L | 4-1 |
| Chile Primera B | 2020/01/15 21:00 | Melipilla v Deportes Copiapo | L | 4-5 |
| Chile Primera B | 2020/01/12 21:00 | Melipilla v Union San Felipe | W | 2-0 |
| Chile Primera B | 2019/10/12 21:00 | Puerto Montt v Melipilla | W | 1-3 |
| Chile Primera B | 2019/10/06 20:00 | Melipilla v Union San Felipe | L | 0-2 |