[7] Guimaraes 1-0 Santa Clara [6] 2021-04-17 14:30
Stadium: Dom Afonso Henriques Round: 27
Referee: Rui Manuel Gomes da Costa Home Manager: Manuel Albino Morim Macaes Away Manager: Daniel Ramos
Head to Head
| Portugal Primeira Liga | 2020/12/21 20:15 | Santa Clara v Guimaraes | W | 0-4 |
| Portugal Cup | 2020/12/13 14:00 | Guimaraes v Santa Clara | L | 0-1 |
| Portugal Primeira Liga | 2020/07/24 18:00 | Santa Clara v Guimaraes | D | 2-2 |
| Portugal Primeira Liga | 2020/01/18 15:30 | Guimaraes v Santa Clara | W | 1-0 |
| Portugal Primeira Liga | 2019/03/30 20:30 | Santa Clara v Guimaraes | L | 1-0 |
| Portugal Primeira Liga | 2018/11/11 15:00 | Guimaraes v Santa Clara | W | 2-0 |
| Europe Friendlies | 2018/07/22 10:00 | Guimaraes v Santa Clara | W | 3-2 |
Home History
| Portugal Primeira Liga | 2021/04/09 19:00 | Portimonense v Guimaraes | L | 3-0 |
| Portugal Primeira Liga | 2021/04/04 16:30 | Guimaraes v Tondela | L | 1-2 |
| Portugal Primeira Liga | 2021/03/20 20:30 | Sporting v Guimaraes | L | 1-0 |
| Portugal Primeira Liga | 2021/03/14 17:30 | Guimaraes v Gil Vicente | L | 2-4 |
| Portugal Primeira Liga | 2021/03/09 21:45 | Braga v Guimaraes | L | 3-0 |
| Portugal Primeira Liga | 2021/02/26 20:30 | Guimaraes v Boavista | W | 2-1 |
| Portugal Primeira Liga | 2021/02/21 15:00 | Pacos Ferreira v Guimaraes | L | 2-1 |
| Portugal Primeira Liga | 2021/02/17 21:45 | Guimaraes v SC Farense | D | 2-2 |
Away History
| Portugal Primeira Liga | 2021/04/11 14:30 | Santa Clara v Nacional | W | 5-1 |
| Portugal Primeira Liga | 2021/04/03 19:30 | FC Porto v Santa Clara | L | 2-1 |
| Portugal Primeira Liga | 2021/03/20 15:30 | Santa Clara v Tondela | D | 1-1 |
| Portugal Primeira Liga | 2021/03/13 18:00 | Santa Clara v Portimonense | W | 2-0 |
| Portugal Primeira Liga | 2021/03/05 20:45 | Sporting v Santa Clara | L | 2-1 |
| Portugal Primeira Liga | 2021/02/27 18:00 | Santa Clara v Pacos Ferreira | W | 3-0 |
| Portugal Primeira Liga | 2021/02/20 17:30 | Gil Vicente v Santa Clara | L | 1-0 |
| Portugal Primeira Liga | 2021/02/14 17:30 | Santa Clara v Braga | L | 0-1 |