[66] Louisville 7-12 Notre Dame [7] 2020-10-17 18:30
Stadium: Notre Dame Stadium Round: 1
Head to Head
| NCAAF | 2019/09/03 00:00 | Notre Dame v Louisville | L | 35-17 |
| NCAAF | 2014/11/22 20:30 | Notre Dame v Louisville | W | 28-31 |
Home History
| NCAAF | 2020/10/09 23:00 | Louisville v Georgia Tech | L | 27-46 |
| NCAAF | 2020/09/26 16:00 | Louisville v Pittsburgh | L | 20-23 |
| NCAAF | 2020/09/19 23:30 | Miami Florida v Louisville | L | 47-34 |
| NCAAF | 2020/09/13 00:00 | Western Kentucky v Louisville | W | 21-35 |
| NCAAF | 2019/12/30 21:00 | Mississippi State v Louisville | W | 28-38 |
| NCAAF | 2019/11/30 17:00 | Louisville v Kentucky | L | 13-45 |
| NCAAF | 2019/11/23 21:00 | Syracuse v Louisville | W | 34-56 |
| NCAAF | 2019/11/17 00:30 | Louisville v NC State | W | 34-20 |
Away History
| NCAAF | 2020/10/10 23:30 | Florida State v Notre Dame | W | 26-42 |
| NCAAF | 2020/09/19 18:30 | South Florida v Notre Dame | W | 0-52 |
| NCAAF | 2020/09/12 18:30 | Duke v Notre Dame | W | 13-27 |
| NCAAF | 2019/12/28 17:00 | Iowa State v Notre Dame | W | 9-33 |
| NCAAF | 2019/11/30 21:00 | Notre Dame v Stanford | W | 45-24 |
| NCAAF | 2019/11/23 19:30 | Boston College v Notre Dame | W | 7-40 |
| NCAAF | 2019/11/16 19:30 | Navy v Notre Dame | W | 20-52 |
| NCAAF | 2019/11/10 00:30 | Notre Dame v Duke | W | 38-7 |