[27] Indiana 24-0 Michigan State [88] 2020-11-14 17:00
Stadium: Spartan Stadium Round: 1
Head to Head
| NCAAF | 2019/09/28 19:30 | Indiana v Michigan State | L | 31-40 |
| NCAAF | 2018/09/22 23:30 | Michigan State v Indiana | L | 35-21 |
| NCAAF | 2017/10/21 19:30 | Indiana v Michigan State | L | 9-17 |
| NCAAF | 2016/10/02 00:00 | Michigan State v Indiana | W | 21-24 |
| NCAAF | 2015/10/24 19:30 | Michigan State v Indiana | L | 52-26 |
| NCAAF | 2014/10/18 19:30 | Indiana v Michigan State | L | 17-56 |
| NCAAF | 2012/10/06 12:00 | Indiana v Michigan State | L | 27-31 |
| NCAAF | 2011/11/19 12:00 | Michigan State v Indiana | L | 55-3 |
Home History
| NCAAF | 2020/11/07 17:00 | Michigan v Indiana | W | 21-38 |
| NCAAF | 2020/10/31 19:30 | Indiana v Rutgers | W | 37-21 |
| NCAAF | 2020/10/24 19:30 | Penn State v Indiana | W | 35-36 |
| NCAAF | 2020/01/03 00:00 | Tennessee v Indiana | L | 23-22 |
| NCAAF | 2019/11/30 17:00 | Indiana v Purdue | W | 44-41 |
| NCAAF | 2019/11/23 20:30 | Michigan v Indiana | L | 39-14 |
| NCAAF | 2019/11/16 17:00 | Indiana v Penn State | L | 27-34 |
| NCAAF | 2019/11/02 23:00 | Northwestern v Indiana | W | 3-34 |
Away History
| NCAAF | 2020/11/07 17:00 | Michigan State v Iowa | L | 7-49 |
| NCAAF | 2020/10/31 16:00 | Michigan State v Michigan | W | 27-24 |
| NCAAF | 2020/10/24 16:00 | Rutgers v Michigan State | L | 38-27 |
| NCAAF | 2019/12/27 20:20 | Michigan State v Wake Forest | W | 27-21 |
| NCAAF | 2019/11/30 20:30 | Maryland v Michigan State | W | 16-19 |
| NCAAF | 2019/11/23 17:00 | Michigan State v Rutgers | W | 27-0 |
| NCAAF | 2019/11/16 17:00 | Michigan State v Michigan | L | 10-44 |
| NCAAF | 2019/11/09 20:30 | Illinois v Michigan State | L | 37-34 |