Louisville 54-99 North Carolina 2021-02-20 23:00
Stadium: Dean Smith Center
Home Manager: Roy Williams Away Manager: Chris Mack
Head to Head
| NCAAB | 2020/02/22 21:00 | North Carolina v Louisville | W | 55-72 |
| NCAAB | 2019/03/14 23:00 | Louisville v North Carolina | L | 70-83 |
| NCAAB | 2019/02/02 19:00 | North Carolina v Louisville | L | 79-69 |
| NCAAB | 2019/01/12 17:00 | Louisville v North Carolina | W | 83-62 |
| NCAAB | 2018/02/18 01:15 | North Carolina v Louisville | L | 93-76 |
| NCAAB | 2017/02/23 02:00 | Louisville v North Carolina | L | 63-74 |
| NCAAB | 2016/02/02 00:00 | Louisville v North Carolina | W | 71-65 |
| NCAAB | 2015/03/12 18:00 | Louisville v North Carolina | L | 60-70 |
Home History
| NCAAB | 2021/02/01 19:00 | Georgia Tech v Louisville | W | 58-74 |
| NCAAB | 2021/01/28 02:00 | Louisville v Clemson | L | 50-54 |
| NCAAB | 2021/01/23 21:00 | Duke v Louisville | W | 65-70 |
| NCAAB | 2021/01/19 00:00 | Florida State v Louisville | L | 78-65 |
| NCAAB | 2021/01/17 01:00 | Louisville v Miami Florida | L | 72-78 |
| NCAAB | 2021/01/14 01:30 | Louisville v Wake Forest | W | 77-65 |
| NCAAB | 2021/01/06 23:30 | Virginia Tech v Louisville | W | 71-73 |
| NCAAB | 2021/01/02 17:00 | Louisville v Boston College | W | 76-64 |
Away History
| NCAAB | 2021/02/18 00:00 | Northeastern v North Carolina | W | 62-82 |
| NCAAB | 2021/02/13 23:00 | North Carolina v Virginia | L | 48-60 |
| NCAAB | 2021/02/06 23:00 | North Carolina v Duke | W | 91-87 |
| NCAAB | 2021/02/03 00:00 | North Carolina v Clemson | L | 50-63 |
| NCAAB | 2021/01/27 00:00 | North Carolina v Pittsburgh | W | 75-65 |
| NCAAB | 2021/01/23 19:00 | NC State v North Carolina | W | 76-86 |
| NCAAB | 2021/01/21 00:00 | Wake Forest v North Carolina | W | 73-80 |
| NCAAB | 2021/01/16 17:00 | North Carolina v Florida State | L | 75-82 |