Duke 65-70 Louisville 2021-01-23 21:00
Stadium: KFC Yum! Center
Home Manager: Chris Mack Away Manager: Mike Krzyzewski
Head to Head
| NCAAB | 2020/01/18 23:00 | Louisville v Duke | L | 79-73 |
| NCAAB | 2019/02/13 02:00 | Duke v Louisville | W | 71-69 |
| NCAAB | 2018/02/22 02:00 | Louisville v Duke | W | 56-82 |
| NCAAB | 2017/03/09 19:30 | Duke v Louisville | W | 81-77 |
| NCAAB | 2017/01/14 17:00 | Duke v Louisville | L | 69-78 |
| NCAAB | 2016/02/20 17:00 | Louisville v Duke | L | 71-64 |
| NCAAB | 2016/02/09 00:00 | Duke v Louisville | W | 72-65 |
| NCAAB | 2015/01/17 17:00 | Louisville v Duke | W | 52-63 |
Home History
| NCAAB | 2021/01/20 02:00 | Duke v Pittsburgh | L | 73-79 |
| NCAAB | 2021/01/13 00:00 | Duke v Virginia Tech | L | 67-74 |
| NCAAB | 2021/01/09 17:00 | Wake Forest v Duke | W | 68-79 |
| NCAAB | 2021/01/07 01:30 | Boston College v Duke | W | 82-83 |
| NCAAB | 2020/12/17 02:00 | Duke v Notre Dame | W | 75-65 |
| NCAAB | 2020/12/09 02:30 | Illinois v Duke | L | 83-68 |
| NCAAB | 2020/12/05 00:00 | Bellarmine v Duke | W | 54-76 |
| NCAAB | 2020/12/02 00:30 | Michigan State v Duke | L | 75-69 |
Away History
| NCAAB | 2021/01/19 00:00 | Florida State v Louisville | L | 78-65 |
| NCAAB | 2021/01/17 01:00 | Louisville v Miami Florida | L | 72-78 |
| NCAAB | 2021/01/14 01:30 | Louisville v Wake Forest | W | 77-65 |
| NCAAB | 2021/01/06 23:30 | Virginia Tech v Louisville | W | 71-73 |
| NCAAB | 2021/01/02 17:00 | Louisville v Boston College | W | 76-64 |
| NCAAB | 2020/12/26 18:00 | Kentucky v Louisville | W | 59-62 |
| NCAAB | 2020/12/23 00:00 | Louisville v Pittsburgh | W | 64-54 |
| NCAAB | 2020/12/19 17:00 | Louisville v Wisconsin | L | 48-85 |