Stadium: Leavey Center
Home Manager: Herb Sendek Away Manager: Sam Scholl
| NCAAB | 2021/01/17 22:00 | Santa Clara v San Diego | L | 69-63 |
| NCAAB | 2020/01/25 23:00 | Santa Clara v San Diego | L | 65-52 |
| NCAAB | 2020/01/04 22:00 | San Diego v Santa Clara | L | 63-80 |
| NCAAB | 2019/03/09 04:20 | San Diego v Santa Clara | W | 62-45 |
| NCAAB | 2019/01/04 03:00 | San Diego v Santa Clara | L | 56-68 |
| NCAAB | 2018/02/10 21:00 | San Diego v Santa Clara | L | 64-70 |
| NCAAB | 2018/01/26 03:00 | Santa Clara v San Diego | W | 58-66 |
| NCAAB | 2017/02/19 04:00 | Santa Clara v San Diego | W | 58-60 |
| NCAAB | 2021/01/29 02:00 | Gonzaga v San Diego | L | 90-62 |
| NCAAB | 2021/01/23 22:00 | San Diego v Portland | W | 78-70 |
| NCAAB | 2021/01/20 02:00 | San Diego v Loyola Marymount | L | 69-72 |
| NCAAB | 2021/01/17 22:00 | Santa Clara v San Diego | L | 69-63 |
| NCAAB | 2020/12/31 22:00 | San Diego v San Francisco | L | 62-70 |
| NCAAB | 2020/12/20 00:00 | San Diego v UC Irvine | L | 53-85 |
| NCAAB | 2020/12/16 23:00 | San Diego v Cal Poly SLO | W | 70-61 |
| NCAAB | 2020/12/15 02:00 | Nevada v San Diego | L | 79-72 |
| NCAAB | 2021/02/17 02:00 | Loyola Marymount v Santa Clara | L | 76-73 |
| NCAAB | 2021/01/24 00:00 | Santa Clara v Loyola Marymount | W | 72-69 |
| NCAAB | 2021/01/22 03:00 | San Francisco v Santa Clara | L | 73-50 |
| NCAAB | 2021/01/17 22:00 | Santa Clara v San Diego | W | 69-63 |
| NCAAB | 2021/01/14 22:00 | Santa Clara v Pacific | L | 58-79 |
| NCAAB | 2021/01/10 00:00 | Santa Clara v Saint Mary's CA | W | 66-64 |
| NCAAB | 2020/12/30 00:00 | Santa Clara v USC Trojans | L | 63-86 |
| NCAAB | 2020/12/22 21:00 | Santa Clara v Colorado State | L | 57-70 |