Stadium: CFSB Center
Home Manager: Matt McMahon Away Manager: Brian Barone
| NCAAB | 2021/02/15 22:00 | Murray State v SIU Edwardsville | L | 86-57 |
| NCAAB | 2020/02/22 20:00 | Murray State v SIU Edwardsville | L | 59-58 |
| NCAAB | 2020/02/02 01:00 | SIU Edwardsville v Murray State | L | 55-74 |
| NCAAB | 2019/02/10 01:00 | SIU Edwardsville v Murray State | L | 55-86 |
| NCAAB | 2019/01/20 01:00 | Murray State v SIU Edwardsville | L | 82-72 |
| NCAAB | 2018/02/10 19:00 | Murray State v SIU Edwardsville | L | 75-66 |
| NCAAB | 2017/12/31 01:00 | SIU Edwardsville v Murray State | L | 63-87 |
| NCAAB | 2017/02/17 00:00 | SIU Edwardsville v Murray State | L | 73-84 |
| NCAAB | 2021/02/19 01:30 | SIU Edwardsville v Austin Peay | L | 57-79 |
| NCAAB | 2021/02/15 22:00 | Murray State v SIU Edwardsville | L | 86-57 |
| NCAAB | 2021/02/13 22:00 | SIU Edwardsville v Jacksonville St | L | 60-80 |
| NCAAB | 2021/02/12 02:00 | SIU Edwardsville v Tennessee Tech | W | 81-63 |
| NCAAB | 2021/02/08 20:00 | Eastern Kentucky v SIU Edwardsville | L | 78-74 |
| NCAAB | 2021/02/06 18:30 | Belmont v SIU Edwardsville | L | 94-62 |
| NCAAB | 2021/02/04 19:00 | Tennessee State v SIU Edwardsville | W | 60-68 |
| NCAAB | 2021/02/02 23:00 | Eastern Illinois v SIU Edwardsville | L | 70-61 |
| NCAAB | 2021/02/19 01:30 | Eastern Illinois v Murray State | L | 68-59 |
| NCAAB | 2021/02/15 22:00 | Murray State v SIU Edwardsville | W | 86-57 |
| NCAAB | 2021/02/14 01:30 | Tennessee Martin v Murray State | W | 55-84 |
| NCAAB | 2021/02/12 23:00 | SE Missouri State v Murray State | W | 60-80 |
| NCAAB | 2021/02/06 21:00 | Murray State v Eastern Kentucky | W | 76-64 |
| NCAAB | 2021/02/05 00:00 | Murray State v Morehead State | L | 56-66 |
| NCAAB | 2021/02/02 00:00 | Murray State v SE Missouri State | W | 77-60 |
| NCAAB | 2021/01/31 01:30 | Belmont v Murray State | L | 72-71 |